BIOMAT Database Logo BIOMAT Database Logo

Stereoselectivity in bioaccumulation and excretion of epoxiconazole by mealworm beetle (Tenebrio molitor) larvae. 2014

Xiaotian Lv, and Chen Liu, and Yaobin Li, and Yongxin Gao, and Huili Wang, and Jianzhong Li, and Baoyuan Guo
Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, China.

Stereoselectivity in bioaccumulation and excretion of stereoisomers of epoxiconazole by mealworm beetle (Tenebrio molitor) larvae through dietary exposure was investigated. Liquid chromatography tandem mass spectrometry (HPLC-MS/MS) method that use a ChiralcelOD-3R[cellulosetris-Tris-(3, 5-dichlorophenyl-carbamate)] chromatography column was applied to carry out chiral separation of the stereoisomers. Wheat bran was spiked with racemic epoxiconazole at two dose levels of 20mg/kg and 2mg/kg (dry weight) to feed T. molitor larvae. The results showed that both the doses of epoxiconazole were taken up by Tenebrio molitor larvae rapidly at the initial stages. There was a significant trend of stereoselective bioaccumulation in the larvae with a preferential accumulation of (-)-epoxiconazole in the 20mg/kg dose. The stereoselectivity in bioaccumulation in the 2mg/kg dosage was not obvious compared to the 20mg/kg group. Results of excretion indicated an active excretion is an important pathway for the larvae to eliminate epoxiconazole which was a passive transport process with non stereoselectivity. The faster elimination might be the reason for the low accumulation of epoxiconazole, as measured by bioaccumulation factor (BAF).

UI MeSH Term Description Entries
D007814 Larva Wormlike or grublike stage, following the egg in the life cycle of insects, worms, and other metamorphosing animals. Maggots,Tadpoles,Larvae,Maggot,Tadpole
D001835 Body Weight The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms. Body Weights,Weight, Body,Weights, Body
D004032 Diet Regular course of eating and drinking adopted by a person or animal. Diets
D004852 Epoxy Compounds Organic compounds that include a cyclic ether with three ring atoms in their structure. They are commonly used as precursors for POLYMERS such as EPOXY RESINS. Epoxide,Epoxides,Epoxy Compound,Oxiranes,Compound, Epoxy,Compounds, Epoxy
D005659 Fungicides, Industrial Chemicals that kill or inhibit the growth of fungi in agricultural applications, on wood, plastics, or other materials, in swimming pools, etc. Industrial Fungicides
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D013237 Stereoisomerism The phenomenon whereby compounds whose molecules have the same number and kind of atoms and the same atomic arrangement, but differ in their spatial relationships. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed) Molecular Stereochemistry,Stereoisomers,Stereochemistry, Molecular,Stereoisomer
D013712 Tenebrio A genus of beetles which infests grain products. Its larva is called mealworm. Mealworm,Mealworms,Tenebrios
D014230 Triazoles Heterocyclic compounds containing a five-membered ring with two carbon atoms and three nitrogen atoms with the molecular formula C2H3N3. Triazole
D053719 Tandem Mass Spectrometry A mass spectrometry technique using two (MS/MS) or more mass analyzers. With two in tandem, the precursor ions are mass-selected by a first mass analyzer, and focused into a collision region where they are then fragmented into product ions which are then characterized by a second mass analyzer. A variety of techniques are used to separate the compounds, ionize them, and introduce them to the first mass analyzer. For example, for in GC-MS/MS, GAS CHROMATOGRAPHY-MASS SPECTROMETRY is involved in separating relatively small compounds by GAS CHROMATOGRAPHY prior to injecting them into an ionization chamber for the mass selection. Mass Spectrometry-Mass Spectrometry,Mass Spectrometry Mass Spectrometry,Mass Spectrometry, Tandem

Related Publications

Xiaotian Lv, and Chen Liu, and Yaobin Li, and Yongxin Gao, and Huili Wang, and Jianzhong Li, and Baoyuan Guo
Enantiomerization and stereoselectivity in bioaccumulation of furalaxyl in Tenebrio molitor larvae.
November 2017, Ecotoxicology and environmental safety,
Xiaotian Lv, and Chen Liu, and Yaobin Li, and Yongxin Gao, and Huili Wang, and Jianzhong Li, and Baoyuan Guo
Dissemination of Fusarium proliferatum by mealworm beetle Tenebrio molitor.
January 2018, PloS one,
Xiaotian Lv, and Chen Liu, and Yaobin Li, and Yongxin Gao, and Huili Wang, and Jianzhong Li, and Baoyuan Guo
Sex pheromone of the mealworm beetle (Tenebrio molitor).
February 1967, The Journal of experimental zoology,
Xiaotian Lv, and Chen Liu, and Yaobin Li, and Yongxin Gao, and Huili Wang, and Jianzhong Li, and Baoyuan Guo
Dietary zinc enrichment reduces the cadmium burden of mealworm beetle (Tenebrio molitor) larvae.
November 2020, Scientific reports,
Xiaotian Lv, and Chen Liu, and Yaobin Li, and Yongxin Gao, and Huili Wang, and Jianzhong Li, and Baoyuan Guo
[Virus diseases in larvae of the mealworm, Tenebrio molitor].
September 1969, Die Naturwissenschaften,
Xiaotian Lv, and Chen Liu, and Yaobin Li, and Yongxin Gao, and Huili Wang, and Jianzhong Li, and Baoyuan Guo
Elemental concentration in mealworm beetle (Tenebrio molitor L.) during metamorphosis.
July 2013, Biological trace element research,
Xiaotian Lv, and Chen Liu, and Yaobin Li, and Yongxin Gao, and Huili Wang, and Jianzhong Li, and Baoyuan Guo
Multiple sex pheromones of the mealworm beetle, Tenebrio molitor L.
April 1969, Nature,
Xiaotian Lv, and Chen Liu, and Yaobin Li, and Yongxin Gao, and Huili Wang, and Jianzhong Li, and Baoyuan Guo
Subcellular partitioning of cadmium and zinc in mealworm beetle (Tenebrio molitor) larvae exposed to metal-contaminated flour.
November 2016, Ecotoxicology and environmental safety,
Xiaotian Lv, and Chen Liu, and Yaobin Li, and Yongxin Gao, and Huili Wang, and Jianzhong Li, and Baoyuan Guo
Vitellogenesis in virgin and mated females of the mealworm beetle, Tenebrio molitor.
January 1996, Acta biochimica Polonica,
Xiaotian Lv, and Chen Liu, and Yaobin Li, and Yongxin Gao, and Huili Wang, and Jianzhong Li, and Baoyuan Guo
Endogenous egg immune defenses in the yellow mealworm beetle (Tenebrio molitor).
May 2017, Developmental and comparative immunology,
Copied contents to your clipboard!