[Dynamics of inflammatory mediators and indices of antiendotoxic immunity in children with purulent-destructive pneumonia]. 2014

L F Pritulo, and Iu A Bisiuk

There were examined 220 children, in whom purulent-destructive pneumonia (PDP) was diagnosed. Level of anti-inflammatory mediators and indices of the antiendotoxine immunity was determined in the blood serum, using immunoassay analysis, after admittance to hospital. There was established, that in PDP in children the concentration of anti-inflammatory mediators interleucines (IL--1 beta, IL-6) is enhanced, as well as of the tumor necrosis factor-- alpha (TNF-alpha), C-reactive protein (CRP), while titre of antibodies to endotoxine class G lowers, and the level of lipopolisaccharid-binded protein (LBP) and soluble form of CD14 receptor (sCD14) is raised, not depending from the patient state severity.

UI MeSH Term Description Entries
D007223 Infant A child between 1 and 23 months of age. Infants
D007700 Kinetics The rate dynamics in chemical or physical systems.
D009336 Necrosis The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
D002097 C-Reactive Protein A plasma protein that circulates in increased amounts during inflammation and after tissue damage. C-Reactive Protein measured by more sensitive methods often for coronary heart disease risk assessment is referred to as High Sensitivity C-Reactive Protein (hs-CRP). High Sensitivity C-Reactive Protein,hs-CRP,hsCRP,C Reactive Protein,High Sensitivity C Reactive Protein
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D002675 Child, Preschool A child between the ages of 2 and 5. Children, Preschool,Preschool Child,Preschool Children
D003627 Data Interpretation, Statistical Application of statistical procedures to analyze specific observed or assumed facts from a particular study. Data Analysis, Statistical,Data Interpretations, Statistical,Interpretation, Statistical Data,Statistical Data Analysis,Statistical Data Interpretation,Analyses, Statistical Data,Analysis, Statistical Data,Data Analyses, Statistical,Interpretations, Statistical Data,Statistical Data Analyses,Statistical Data Interpretations
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D012720 Severity of Illness Index Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder. Illness Index Severities,Illness Index Severity

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