Biomaterial Database

Heterogeneous copper-catalyzed hydroxylation of aryl iodides under air conditions. 2014

Guodong Ding, and Hongling Han, and Tao Jiang, and Tianbin Wu, and Buxing Han

Institute of Chemistry, Chinese Academy of Sciences, Zhongguancun North First Street 2, 100190 Beijing, PR China. Jiangt@iccas.ac.cn Hanbx@iccas.ac.cn.

In this work, the ligand-free heterogeneous copper Cu-g-C3N4 was synthesized and used for the hydroxylation of aryl iodides to synthesize phenols using cheap bases. The catalyst was conveniently prepared, air-tolerant, reusable and scalable, and is very efficient for a wide range of substrates. The synthesis of substituted phenols can be carried out under air conditions and has great potential for practical applications.

UI	MeSH Term	Description	Entries
D007462	Iodobenzenes	Any derivative of BENZENE that contains IODINE.
D008024	Ligands	A molecule that binds to another molecule, used especially to refer to a small molecule that binds specifically to a larger molecule, e.g., an antigen binding to an antibody, a hormone or neurotransmitter binding to a receptor, or a substrate or allosteric effector binding to an enzyme. Ligands are also molecules that donate or accept a pair of electrons to form a coordinate covalent bond with the central metal atom of a coordination complex. (From Dorland, 27th ed)	Ligand
D010636	Phenols	Benzene derivatives that include one or more hydroxyl groups attached to the ring structure.
D002384	Catalysis	The facilitation of a chemical reaction by material (catalyst) that is not consumed by the reaction.	Catalyses
D003300	Copper	A heavy metal trace element with the atomic symbol Cu, atomic number 29, and atomic weight 63.55.	Copper-63,Copper 63
D006900	Hydroxylation	Placing of a hydroxyl group on a compound in a position where one did not exist before. (Stedman, 26th ed)	Hydroxylations
D000388	Air	The mixture of gases present in the earth's atmosphere consisting of oxygen, nitrogen, carbon dioxide, and small amounts of other gases.