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Copper-catalyzed synthesis of mixed alkyl aryl phosphonates. 2014

Martín Fañanás-Mastral, and Ben L Feringa
Stratingh Institute for Chemistry, University of Groningen , Nijenborgh 4, 9747 AG Groningen, The Netherlands.

Copper-catalysis allows the direct oxygen-arylation of dialkyl phosphonates with diaryliodonium salts. This novel methodology proceeds with a wide range of phosphonates and phosphoramidates under mild conditions and gives straightforward access to valuable mixed alkyl aryl phosphonates in very good yields and near perfect selectivity.

UI MeSH Term Description Entries

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