OBJECTIVE An isotope internal standard analytical process has been developed for the determination of phthalates (PAEs) in Chinese spirits by gas chromatography-mass spectrometry (GC-MS). METHODS The samples alcoholicity were pre-adjusted after D4-internal standard adjunction, then were extracted with toluene. The supernatant were determined by GC-MS. RESULTS The calibration curves of 16 phthalates obtained were linear with correlation coefficients greater than 0.997. The calibration curves range from 0.05 - 2 microg/ml. It was effective in the determination of phthalates in Chinese spirits with recoveries of 81.8% - 120% and RSD of 0.711% - 6.63%. The limit of quantification were 0.005 - 0.05 microg/ml. CONCLUSIONS The pre-treatment of the process was simple and fast meanwhile the determination was precise. The method has a highly sensitivity. It's suitable for all kinds of phthalates chinese spirits detection.