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NanoKeepers: stimuli responsive nanocapsules for programmed specific targeting and drug delivery. 2014
Frank J Hernandez, and
Luiza I Hernandez, and
Murat Kavruk, and
Yakup M Arıca, and
Gülay Bayramoğlu, and
Baris A Borsa, and
Hüseyin A Öktem, and
Thomas Schäfer, and
Veli C Özalp
POLYMAT, University of Basque Country UPV/EHU, Avda. Tolosa 72, 20018 Donostia-San Sebastián, Spain. frank.hernandez@polymat.eu.
Bacterial resistance is a high priority clinical issue worldwide. Thus, an effective system that rapidly provides specific treatment for bacterial infections using controlled dose release remains an unmet clinical need. Herein, we report on the NanoKeepers approach for the specific targeting of S. aureus with controlled release of antibiotics based on nuclease activity.
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