Biomaterial Database

CRISPR bacon: a sizzling technique to generate genetically engineered pigs. 2014

Franco J DeMayo, and Thomas E Spencer, and

Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas.

UI	MeSH Term	Description	Entries
D008460	Meat	The edible portions of any animal used for food including cattle, swine, goats/sheep, poultry, fish, shellfish, and game.	Meats
D005818	Genetic Engineering	Directed modification of the gene complement of a living organism by such techniques as altering the DNA, substituting genetic material by means of a virus, transplanting whole nuclei, transplanting cell hybrids, etc.	Genetic Intervention,Engineering, Genetic,Intervention, Genetic,Genetic Interventions,Interventions, Genetic
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D055786	Gene Knockout Techniques	Techniques to alter a gene sequence that result in an inactivated gene, or one in which the expression can be inactivated at a chosen time during development to study the loss of function of a gene.	Gene Knock-Out Techniques,Gene Knock Out,Gene Knock Out Techniques,Gene Knockout,Gene Knock Outs,Gene Knock-Out Technique,Gene Knockout Technique,Gene Knockouts,Knock Out, Gene,Knock Outs, Gene,Knock-Out Technique, Gene,Knock-Out Techniques, Gene,Knockout Technique, Gene,Knockout Techniques, Gene,Knockout, Gene,Knockouts, Gene,Out, Gene Knock,Outs, Gene Knock,Technique, Gene Knock-Out,Technique, Gene Knockout,Techniques, Gene Knock-Out,Techniques, Gene Knockout
D055879	Gene Knock-In Techniques	Techniques used to add in exogenous gene sequence such as mutated genes; REPORTER GENES, to study mechanisms of gene expression; or regulatory control sequences, to study effects of temporal changes to GENE EXPRESSION.	Gene Knock In,Gene Knock In Techniques,Gene Knock-In,Gene Knock Ins,Gene Knock-In Technique,Gene Knock-Ins,In, Gene Knock,Ins, Gene Knock,Knock In, Gene,Knock Ins, Gene,Knock-In Technique, Gene,Knock-In Techniques, Gene,Knock-In, Gene,Knock-Ins, Gene,Technique, Gene Knock-In,Techniques, Gene Knock-In
D059765	Homologous Recombination	An exchange of DNA between matching or similar sequences.	Homologous Recombinations,Recombination, Homologous,Recombinations, Homologous
D030801	Animals, Genetically Modified	ANIMALS whose GENOME has been altered by GENETIC ENGINEERING, or their offspring.	Animals, Transgenic,Genetically Modified Animals,Transgenic Animals,Founder Animals, Transgenic,GMO Animals,Genetically Engineered Animals,Animal, GMO,Animal, Genetically Engineered,Animal, Genetically Modified,Animal, Transgenic,Animal, Transgenic Founder,Animals, GMO,Animals, Genetically Engineered,Animals, Transgenic Founder,Engineered Animal, Genetically,Engineered Animals, Genetically,Founder Animal, Transgenic,GMO Animal,Genetically Engineered Animal,Genetically Modified Animal,Modified Animal, Genetically,Modified Animals, Genetically,Transgenic Animal,Transgenic Founder Animal,Transgenic Founder Animals
D030841	Food, Genetically Modified	Food derived from genetically modified organisms (ORGANISMS, GENETICALLY MODIFIED).	Genetically Modified Food,GMO Food,Food, GMO,Foods, GMO,Foods, Genetically Modified,GMO Foods,Genetically Modified Foods
D034421	Sus scrofa	A species of SWINE, in the family Suidae, comprising a number of subspecies including the domestic pig Sus scrofa domestica.	Pig, Domestic,Sus scrofa domesticus,Wild Boar,Sus scrofa domestica,Boar, Wild,Boars, Wild,Domestic Pig,Domestic Pigs,Pigs, Domestic,Wild Boars
D064113	CRISPR-Cas Systems	Adaptive antiviral defense mechanisms, in archaea and bacteria, based on DNA repeat arrays called CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS (CRISPR elements) that function in conjunction with CRISPR-ASSOCIATED PROTEINS (Cas proteins). Several types have been distinguished, including Type I, Type II, and Type III, based on signature motifs of CRISPR-ASSOCIATED PROTEINS.	CRISPR Cas Systems,CRISPR-Cas System,System, CRISPR-Cas,Systems, CRISPR-Cas