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The endogenous inhibin content was measured by radioimmunoassay in segments of seminiferous tubules at specific stages of the spermatogenic cycle isolated by transillumination-assisted dissection as described by Parvinen (1982). In addition, the immunoactive inhibin production in response to FSH stimulation was investigated. The inhibin content was greatest in tubules at stages II-VI of the cycle and was lowest at stages VII-VIII. Over 48 h of culture, the secretion of inhibin into the medium was greatest at stages XIII-VI and lowest at stages VII-VIII. The inhibin response to FSH stimulation was greatest at stages IX-XIII and least at stages VII-VIII. The results demonstrate that the secretion of inhibin by adult tubules in vitro varies according to the stage of the seminiferous cycle.
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G P Risbridger, and
Y H Hodgson, and
P Pöllänen, and
D M de Kretser
January 1982,
Molecular and cellular endocrinology,
G F Gonzales, and
G P Risbridger, and
Y H Hodgson, and
P Pöllänen, and
D M de Kretser
May 1985,
Molecular and cellular endocrinology,
G F Gonzales, and
G P Risbridger, and
Y H Hodgson, and
P Pöllänen, and
D M de Kretser
August 1978,
The Journal of endocrinology,
G F Gonzales, and
G P Risbridger, and
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P Pöllänen, and
D M de Kretser
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G F Gonzales, and
G P Risbridger, and
Y H Hodgson, and
P Pöllänen, and
D M de Kretser
January 1992,
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G F Gonzales, and
G P Risbridger, and
Y H Hodgson, and
P Pöllänen, and
D M de Kretser
January 1975,
Current topics in molecular endocrinology,
G F Gonzales, and
G P Risbridger, and
Y H Hodgson, and
P Pöllänen, and
D M de Kretser
December 1991,
Molecular and cellular endocrinology,
G F Gonzales, and
G P Risbridger, and
Y H Hodgson, and
P Pöllänen, and
D M de Kretser
October 1993,
Fundamental and applied toxicology : official journal of the Society of Toxicology,
G F Gonzales, and
G P Risbridger, and
Y H Hodgson, and
P Pöllänen, and
D M de Kretser
February 1985,
International journal of andrology,
G F Gonzales, and
G P Risbridger, and
Y H Hodgson, and
P Pöllänen, and
D M de Kretser
July 1987,
Endocrinology,
