Biomaterial Database

Studies on an idiopathic syndrome in the brown hare (Lepus europaeus P.) and mountain hare (Lepus timidus L.) in Sweden, with special reference to hepatic lesions. 1989

K Gustafsson, and T Svensson, and A Uggla

At routine post mortem examinations performed at the National Veterinary Institute (NVI), Uppsala, Sweden, during November 1983-May 1984, a syndrome principally characterized by an acute hepatosis was found in 85 out of 177 brown hares (Lepus europaeus P.). The hepatic lesions consisted of periportal or extensive necrosis and haemorrhages. Concomitant changes in other organs were tubular necrosis in the kidneys, acute catarrhal enteritis, severe congestion, oedema and haemorrhages of the lungs, hyperemia of the spleen, and in some cases jaundice. A supplementary retrospective study of liver sections from another 388 brown hares and 202 mountain hares (Lepus timidus L.), autopsied at NVI during 1980-1985, revealed 35 additional cases of the acute hepatosis, 32 being in brown hares and 3 in mountain hares. The histopathology of the liver lesions may suggest a toxic etiology.

UI	MeSH Term	Description	Entries
D007793	Lagomorpha	An order of small mammals comprising two families, Ochotonidae (pikas) and Leporidae (RABBITS and HARES). Head and body length ranges from about 125 mm to 750 mm. Hares and rabbits have a short tail, and the pikas lack a tail. Rabbits are born furless and with both eyes and ears closed. HARES are born fully haired with eyes and ears open. All are vegetarians. (From Nowak, Walker's Mammals of the World, 5th ed, p539-41)	Ochotona,Pikas,Lagomorphs,Leporidae,Ochotonidae,Lagomorph,Pika
D008099	Liver	A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances.	Livers
D008107	Liver Diseases	Pathological processes of the LIVER.	Liver Dysfunction,Disease, Liver,Diseases, Liver,Dysfunction, Liver,Dysfunctions, Liver,Liver Disease,Liver Dysfunctions
D008322	Mammals	Warm-blooded vertebrate animals belonging to the class Mammalia, including all that possess hair and suckle their young.	Mammalia,Mammal
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D012189	Retrospective Studies	Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.	Retrospective Study,Studies, Retrospective,Study, Retrospective
D013577	Syndrome	A characteristic symptom complex.	Symptom Cluster,Cluster, Symptom,Clusters, Symptom,Symptom Clusters,Syndromes