Factors predicting sensory and motor recovery after the repair of upper limb peripheral nerve injuries. 2014

Bo He, and Zhaowei Zhu, and Qingtang Zhu, and Xiang Zhou, and Canbin Zheng, and Pengliang Li, and Shuang Zhu, and Xiaolin Liu, and Jiakai Zhu
Department of Microsurgery and Orthopedic Trauma, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong Province, China.

OBJECTIVE To investigate the factors associated with sensory and motor recovery after the repair of upper limb peripheral nerve injuries. METHODS The online PubMed database was searched for English articles describing outcomes after the repair of median, ulnar, radial, and digital nerve injuries in humans with a publication date between 1 January 1990 and 16 February 2011. METHODS THE FOLLOWING TYPES OF ARTICLE WERE SELECTED: (1) clinical trials describing the repair of median, ulnar, radial, and digital nerve injuries published in English; and (2) studies that reported sufficient patient information, including age, mechanism of injury, nerve injured, injury location, defect length, repair time, repair method, and repair materials. SPSS 13.0 software was used to perform univariate and multivariate logistic regression analyses and to investigate the patient and intervention factors associated with outcomes. METHODS Sensory function was assessed using the Mackinnon-Dellon scale and motor function was assessed using the manual muscle test. Satisfactory motor recovery was defined as grade M4 or M5, and satisfactory sensory recovery was defined as grade S3(+) or S4. RESULTS Seventy-one articles were included in this study. Univariate and multivariate logistic regression analyses showed that repair time, repair materials, and nerve injured were independent predictors of outcome after the repair of nerve injuries (P < 0.05), and that the nerve injured was the main factor affecting the rate of good to excellent recovery. CONCLUSIONS Predictors of outcome after the repair of peripheral nerve injuries include age, gender, repair time, repair materials, nerve injured, defect length, and duration of follow-up.

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