[Lipoprotein Lp(a): a new risk factor of atherogenesis]. 1989

P Davidoff, and E Bruckert, and P Giral, and R Doumith, and F Thervet, and J Truffert, and J L de Gennes
Service d'endocrinologie-métabolisme, l'Hôpital, Paris.

Lp(a) is a lipoprotein present in all individuals in concentrations that are genetically determined. Its structure is characterized by the presence of an apoprotein with a high carbohydrate content called apoprotein a. Since 1972, numerous concordant data have endowed Lp(a) with a high risk of atherogenesis. This risk applies to the coronary and cervico-encephalic arteries. For the latter, Lp(a) even is a lipid parameter regarded as a major risk factor. The origin and metabolism of Lp(a) are little known, by they seem to differ from those of low-density lipoproteins. Its specific apoprotein of Lp(a). At the moment, there is no simple dietetic or medicinal treatment that can lower substantially the serum level of Lp(a).

UI MeSH Term Description Entries
D008074 Lipoproteins Lipid-protein complexes involved in the transportation and metabolism of lipids in the body. They are spherical particles consisting of a hydrophobic core of TRIGLYCERIDES and CHOLESTEROL ESTERS surrounded by a layer of hydrophilic free CHOLESTEROL; PHOSPHOLIPIDS; and APOLIPOPROTEINS. Lipoproteins are classified by their varying buoyant density and sizes. Circulating Lipoproteins,Lipoprotein,Lipoproteins, Circulating
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001161 Arteriosclerosis Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries. Arterioscleroses
D012307 Risk Factors An aspect of personal behavior or lifestyle, environmental exposure, inborn or inherited characteristic, which, based on epidemiological evidence, is known to be associated with a health-related condition considered important to prevent. Health Correlates,Risk Factor Scores,Risk Scores,Social Risk Factors,Population at Risk,Populations at Risk,Correlates, Health,Factor, Risk,Factor, Social Risk,Factors, Social Risk,Risk Factor,Risk Factor Score,Risk Factor, Social,Risk Factors, Social,Risk Score,Score, Risk,Score, Risk Factor,Social Risk Factor
D017270 Lipoprotein(a) A lipoprotein that resembles the LOW-DENSITY LIPOPROTEINS but with an extra protein moiety, APOPROTEIN (A) also known as APOLIPOPROTEIN (A), linked to APOLIPOPROTEIN B-100 on the LDL by one or two disulfide bonds. High plasma level of lipoprotein (a) is associated with increased risk of atherosclerotic cardiovascular disease. Lipoprotein (a),Lipoprotein (a-),Lipoprotein Lp(a),Lipoprotein a

Related Publications

P Davidoff, and E Bruckert, and P Giral, and R Doumith, and F Thervet, and J Truffert, and J L de Gennes
January 1991, Revista medica de Chile,
P Davidoff, and E Bruckert, and P Giral, and R Doumith, and F Thervet, and J Truffert, and J L de Gennes
November 1989, Medicina clinica,
P Davidoff, and E Bruckert, and P Giral, and R Doumith, and F Thervet, and J Truffert, and J L de Gennes
January 1988, Arteriosclerosis (Dallas, Tex.),
P Davidoff, and E Bruckert, and P Giral, and R Doumith, and F Thervet, and J Truffert, and J L de Gennes
November 1986, JAMA,
P Davidoff, and E Bruckert, and P Giral, and R Doumith, and F Thervet, and J Truffert, and J L de Gennes
March 1984, Lebensversicherungs Medizin,
P Davidoff, and E Bruckert, and P Giral, and R Doumith, and F Thervet, and J Truffert, and J L de Gennes
April 1994, Medizinische Klinik (Munich, Germany : 1983),
P Davidoff, and E Bruckert, and P Giral, and R Doumith, and F Thervet, and J Truffert, and J L de Gennes
December 2009, The New England journal of medicine,
P Davidoff, and E Bruckert, and P Giral, and R Doumith, and F Thervet, and J Truffert, and J L de Gennes
January 2002, Lijecnicki vjesnik,
P Davidoff, and E Bruckert, and P Giral, and R Doumith, and F Thervet, and J Truffert, and J L de Gennes
September 1984, Wiener medizinische Wochenschrift (1946),
P Davidoff, and E Bruckert, and P Giral, and R Doumith, and F Thervet, and J Truffert, and J L de Gennes
January 1971, Sudebno-meditsinskaia ekspertiza,
Copied contents to your clipboard!