Validation of a triglyceride meter for use in pregnancy. 2014

Helen L Barrett, and Marloes Dekker Nitert, and Michael D'Emden, and H David McIntyre, and Leonie K Callaway
UQ Centre for Clinical Research, The University of Queensland, Herston, Queensland, Australia. h.barrett@uq.edu.au.

BACKGROUND Elevated maternal triglycerides have been associated with adverse pregnancy outcomes including an increased risk of preeclampsia and macrosomia. A valid triglyceride meter would allow the examination of maternal postprandial triglycerides in a systematic manner. A non-fasting venous and two capillary measurements (using the Roche Accutrend® Plus meter) of triglycerides were measured in 40 participants at a mean of 36 weeks gestation. RESULTS The two methods were highly correlated (r = 0.89, P < 0.0001), and the distributions were similar (mean difference 0.01 mmol/L (SD 0.47)), t = 0.18, P =0.86). Passing Bablok equation was: y =  -0.01 + 0.98 × [95% CI intercept -0.51 - 0. 38; 95% CI slope 0.85-1.15). The estimated bias was -0.01 mmol/L (95% CI -0.93 - 0.91)). CONCLUSIONS This study demonstrated the Accutrend® Plus meter provides results that correlate strongly with the reference method, with low bias, when used in late pregnancy.

UI MeSH Term Description Entries
D011247 Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. Gestation,Pregnancies
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D014280 Triglycerides An ester formed from GLYCEROL and three fatty acid groups. Triacylglycerol,Triacylglycerols,Triglyceride

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