Overall clinico-epidemiological examination revealed a high proportion (11.4%) of rural inhabitants affected with chronic nonspecific diseases of the lung (CNDL) in Uzbekistan. Chronic bronchitis was stated to be the main clinical from of CNDL. It was detected in 9.9% of the inhabitants. Chronic obstructive bronchitis was mainly diagnosed in collective farmers and machine-operators (31%) who, in their activities, were mostly influenced by harmful labour conditions. The maximum volume rate of expiration at 50 and 75% levels and the curve of forced expiration proved to be informative for detection of obstruction in the distal bronchi. Many new cases were registered by the frequency of their referral.