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Haemodynamic and heart weight parameters were compared in male rats exposed to intermittent high-altitude (IHA) hypoxia (barochamber, 8 h/day, 5 days/week, total of 24 exposures stepwise up to 7,000 m) starting either from the 4th day or the 12th week of postnatal life. Systemic arterial pressure and heart rate increased in adult IHA acclimatized animals only. Marked chronic pulmonary hypertension and right ventricular enlargement were found in both age groups. Right ventricular weight increased linearly with a rise of pulmonary blood pressure in animals exposed to IHA from the 4th day of life (r = 0.72); no significant relation was found in adult rats (r = 0.16). The close correlation between both variables in young hypoxic rats may be due to the ability of the developing heart to respond to chronic hypoxia by both hypertrophy and hyperplasia of myocytes.
F Kolár, and
B Ostádal, and
J Procházka, and
V Pelouch, and
J Widimský
January 1984,
Physiologia Bohemoslovaca,
F Kolár, and
B Ostádal, and
J Procházka, and
V Pelouch, and
J Widimský
March 1980,
Chest,
F Kolár, and
B Ostádal, and
J Procházka, and
V Pelouch, and
J Widimský
July 1979,
The Indian journal of medical research,
F Kolár, and
B Ostádal, and
J Procházka, and
V Pelouch, and
J Widimský
March 1977,
Pflugers Archiv : European journal of physiology,
F Kolár, and
B Ostádal, and
J Procházka, and
V Pelouch, and
J Widimský
January 1985,
Physiologia Bohemoslovaca,
F Kolár, and
B Ostádal, and
J Procházka, and
V Pelouch, and
J Widimský
March 1990,
Sbornik lekarsky,
F Kolár, and
B Ostádal, and
J Procházka, and
V Pelouch, and
J Widimský
September 1977,
Virchows Archiv. B, Cell pathology,
F Kolár, and
B Ostádal, and
J Procházka, and
V Pelouch, and
J Widimský
January 2000,
Physiological research,
F Kolár, and
B Ostádal, and
J Procházka, and
V Pelouch, and
J Widimský
January 1981,
Cor et vasa,
F Kolár, and
B Ostádal, and
J Procházka, and
V Pelouch, and
J Widimský
January 1977,
Cor et vasa,
