-transparent.png){kind=logo}
Intravenous injection of beta-endorphin antiserum lowered the threshold of the tail-shock reaction to nociceptive electrocutaneous stimulation in rats in the first 1-2 days and raised it in the following 2-3 months. Naloxone injection reversed the analgesic effect of antiserum to beta-endorphin. Administration of normal serum did not change the threshold of the nociceptive reaction and naloxone failed to alter its effect. It is suggested that the secondary protracted effect of antiserum to beta-endorphin is a result of activation of the endogenous opioid system as a rebound-effect to diminished liberation of beta-endorphin in the first phase of the action of its antiserum.
S V Litvinov, and
V V Aristova, and
Iu A Aristov, and
V V Shul'govskiĭ, and
L V Kaliuzhnyĭ
April 1989,
Biulleten' eksperimental'noi biologii i meditsiny,
S V Litvinov, and
V V Aristova, and
Iu A Aristov, and
V V Shul'govskiĭ, and
L V Kaliuzhnyĭ
January 1985,
Canadian journal of physiology and pharmacology,
S V Litvinov, and
V V Aristova, and
Iu A Aristov, and
V V Shul'govskiĭ, and
L V Kaliuzhnyĭ
March 1987,
Neuroscience letters,
S V Litvinov, and
V V Aristova, and
Iu A Aristov, and
V V Shul'govskiĭ, and
L V Kaliuzhnyĭ
January 1986,
Masui. The Japanese journal of anesthesiology,
S V Litvinov, and
V V Aristova, and
Iu A Aristov, and
V V Shul'govskiĭ, and
L V Kaliuzhnyĭ
January 1989,
Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova,
S V Litvinov, and
V V Aristova, and
Iu A Aristov, and
V V Shul'govskiĭ, and
L V Kaliuzhnyĭ
May 1983,
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.),
S V Litvinov, and
V V Aristova, and
Iu A Aristov, and
V V Shul'govskiĭ, and
L V Kaliuzhnyĭ
October 1980,
European journal of pharmacology,
S V Litvinov, and
V V Aristova, and
Iu A Aristov, and
V V Shul'govskiĭ, and
L V Kaliuzhnyĭ
January 1980,
Lancet (London, England),
S V Litvinov, and
V V Aristova, and
Iu A Aristov, and
V V Shul'govskiĭ, and
L V Kaliuzhnyĭ
August 1976,
Proceedings of the National Academy of Sciences of the United States of America,
S V Litvinov, and
V V Aristova, and
Iu A Aristov, and
V V Shul'govskiĭ, and
L V Kaliuzhnyĭ
February 1977,
Proceedings of the National Academy of Sciences of the United States of America,
