Intestinal colonization among very low birth weight infants in first week of life. 2014

Sourabh Dutta, and Meenakshi Ganesh, and Pallab Ray, and Anil Narang
Departments of Pediatrics and *Medical Microbiology, Postgraduate Institute of Medical Education and Research, Chandigarh, India. Correspondence to: Dr Sourabh Dutta, Additional Professor, Division of Neonatology, Department of Pediatrics, PGIMER, Chandigarh 160 012, India. sourabhdutta@yahoo.co.in.

OBJECTIVE To study intestinal colonization patterns in very low birth weight infants in the first week of life in a neonatal intensive care unit. METHODS Meconium/stool specimens were obtained on days 1, 3, 5 and 7 from 38 very low-birth-weight infants in a level III neonatal intensive care unit. RESULTS On day 1, 45% had sterile guts, and by day 3, all infants were colonized. E. coli, K. pneumoniae and Enterococcus fecalis were predominant organisms. Lactobacilli was found in one isolate and Bifidobacteria was not detected during the study period. There was an association between formula feeding and E. coli colonization. CONCLUSIONS Very low birth weight infants admitted in neonatal intensive care units have abnormal intestinal colonization patterns.

UI MeSH Term Description Entries
D007194 India A country in southern Asia, bordering the Arabian Sea and the Bay of Bengal, between Burma and Pakistan. The capitol is New Delhi. Republic of India
D007231 Infant, Newborn An infant during the first 28 days after birth. Neonate,Newborns,Infants, Newborn,Neonates,Newborn,Newborn Infant,Newborn Infants
D008470 Meconium The thick green-to-black mucilaginous material found in the intestines of a full-term fetus. It consists of secretions of the INTESTINAL GLANDS; BILE PIGMENTS; FATTY ACIDS; AMNIOTIC FLUID; and intrauterine debris. It constitutes the first stools passed by a newborn. Meconiums
D011446 Prospective Studies Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group. Prospective Study,Studies, Prospective,Study, Prospective
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001419 Bacteria One of the three domains of life (the others being Eukarya and ARCHAEA), also called Eubacteria. They are unicellular prokaryotic microorganisms which generally possess rigid cell walls, multiply by cell division, and exhibit three principal forms: round or coccal, rodlike or bacillary, and spiral or spirochetal. Bacteria can be classified by their response to OXYGEN: aerobic, anaerobic, or facultatively anaerobic; by the mode by which they obtain their energy: chemotrophy (via chemical reaction) or PHOTOTROPHY (via light reaction); for chemotrophs by their source of chemical energy: CHEMOLITHOTROPHY (from inorganic compounds) or chemoorganotrophy (from organic compounds); and by their source for CARBON; NITROGEN; etc.; HETEROTROPHY (from organic sources) or AUTOTROPHY (from CARBON DIOXIDE). They can also be classified by whether or not they stain (based on the structure of their CELL WALLS) with CRYSTAL VIOLET dye: gram-negative or gram-positive. Eubacteria
D019102 Infant, Very Low Birth Weight An infant whose weight at birth is less than 1500 grams (3.3 lbs), regardless of gestational age. Very Low Birth Weight,Very-Low-Birth-Weight Infant,Infant, Very-Low-Birth-Weight,Infants, Very-Low-Birth-Weight,Very Low Birth Weight Infant,Very-Low-Birth-Weight Infants
D064307 Microbiota The full collection of microbes (bacteria, fungi, virus, etc.) that naturally exist within a particular biological niche such as an organism, soil, a body of water, etc. Human Microbiome,Microbiome,Microbiome, Human,Microbial Community,Microbial Community Composition,Microbial Community Structure,Community Composition, Microbial,Community Structure, Microbial,Community, Microbial,Composition, Microbial Community,Human Microbiomes,Microbial Communities,Microbial Community Compositions,Microbial Community Structures,Microbiomes,Microbiotas

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