BIOMAT Database Logo BIOMAT Database Logo

Spontaneous dislocation of a crystalline lens to the anterior chamber with pupillary block glaucoma in Noonan Syndrome: a case report. 2014

Udayaditya Mukhopadhyaya, and Chandana Chakraborti, and Anindita Mondal, and Ujjal Pattyanayak, and Rajesh Kumar Agarwal, and Partha Tripathi
Regional Institute Of Ophthalmology(RIO), Kolkata, Kolkata 700073, West Bengal, India.

We report a 13-year-old child with Noonan Syndrome who developed spontaneous dislocation of the crystalline lens in anterior chamber leading to pupillary block glaucoma in the left eye and subluxation of lens in right eye. Intracapsular extraction of the dislocated lens was done in the left eye. Prompt diagnosis and management is needed in such cases to avoid glaucoma and corneal endothelial cell damage. We could not find any such case after thorough Medline search.

UI MeSH Term Description Entries
D007906 Lens Subluxation Incomplete rupture of the zonule with the displaced lens remaining behind the pupil. In dislocation, or complete rupture, the lens is displaced forward into the anterior chamber or backward into the vitreous body. When congenital, this condition is known as ECTOPIA LENTIS. Lens Dislocation,Lens Dislocation and Subluxation,Dislocation, Lens,Dislocations, Lens,Lens Dislocations,Lens Subluxations,Subluxation, Lens,Subluxations, Lens
D008297 Male Males
D009634 Noonan Syndrome A genetically heterogeneous, multifaceted disorder characterized by short stature, webbed neck, ptosis, skeletal malformations, hypertelorism, hormonal imbalance, CRYPTORCHIDISM, multiple cardiac abnormalities (most commonly including PULMONARY VALVE STENOSIS), and some degree of INTELLECTUAL DISABILITY. The phenotype bears similarities to that of TURNER SYNDROME that occurs only in females and has its basis in a 45, X karyotype abnormality. Noonan syndrome occurs in both males and females with a normal karyotype (46,XX and 46,XY). Mutations in a several genes (PTPN11, KRAS, SOS1, NF1 and RAF1) have been associated the NS phenotype. Mutations in PTPN11 are the most common. LEOPARD SYNDROME, a disorder that has clinical features overlapping those of Noonan Syndrome, is also due to mutations in PTPN11. In addition, there is overlap with the syndrome called neurofibromatosis-Noonan syndrome due to mutations in NF1. Male Turner Syndrome,Turner Syndrome, Male,Familial Turner Syndrome,Female Pseudo-Turner Syndrome,Noonan Syndrome 1,Noonan-Ehmke Syndrome,Pseudo-Ullrich-Turner Syndrome,Turner Phenotype with Normal Karyotype,Turner's Phenotype, Karyotype Normal,Turner's Syndrome, Male,Turner-Like Syndrome,Ullrich-Noonan Syndrome,Female Pseudo Turner Syndrome,Male Turner's Syndrome,Noonan Ehmke Syndrome,Pseudo Ullrich Turner Syndrome,Pseudo-Turner Syndrome, Female,Turner Like Syndrome,Turner Syndrome, Familial,Ullrich Noonan Syndrome
D003241 Consanguinity The magnitude of INBREEDING in humans. Inbreeding, Human,Consanguineous Marriage,Consanguinous Mating,Consanguineous Marriages,Consanguinities,Consanguinous Matings,Human Inbreeding,Human Inbreedings,Inbreedings, Human,Marriage, Consanguineous,Marriages, Consanguineous,Mating, Consanguinous,Matings, Consanguinous
D005139 Eyeglasses A pair of ophthalmic lenses in a frame or mounting which is supported by the nose and ears. The purpose is to aid or improve vision. It does not include goggles or nonprescription sun glasses for which EYE PROTECTIVE DEVICES is available. Glasses,Spectacles,Sun Glasses, Prescription,Glasses, Prescription Sun,Prescription Sun Glasses
D005145 Face The anterior portion of the head that includes the skin, muscles, and structures of the forehead, eyes, nose, mouth, cheeks, and jaw. Faces
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000015 Abnormalities, Multiple Congenital abnormalities that affect more than one organ or body structure. Multiple Abnormalities
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D000867 Anterior Chamber The space in the eye, filled with aqueous humor, bounded anteriorly by the cornea and a small portion of the sclera and posteriorly by a small portion of the ciliary body, the iris, and that part of the crystalline lens which presents through the pupil. (Cline et al., Dictionary of Visual Science, 4th ed, p109) Anterior Chambers,Chamber, Anterior,Chambers, Anterior

Related Publications

Udayaditya Mukhopadhyaya, and Chandana Chakraborti, and Anindita Mondal, and Ujjal Pattyanayak, and Rajesh Kumar Agarwal, and Partha Tripathi
Simple technique to abort pupillary block glaucoma secondary to anterior chamber crystalline lens dislocation in Marfan's syndrome.
December 2013, Clinical & experimental ophthalmology,
Udayaditya Mukhopadhyaya, and Chandana Chakraborti, and Anindita Mondal, and Ujjal Pattyanayak, and Rajesh Kumar Agarwal, and Partha Tripathi
Bilateral spontaneous crystalline lens dislocation to the anterior chamber: a case report.
January 2013, Srpski arhiv za celokupno lekarstvo,
Udayaditya Mukhopadhyaya, and Chandana Chakraborti, and Anindita Mondal, and Ujjal Pattyanayak, and Rajesh Kumar Agarwal, and Partha Tripathi
[Reverse pupillary block following anterior crystalline lens dislocation].
December 2012, Klinische Monatsblatter fur Augenheilkunde,
Udayaditya Mukhopadhyaya, and Chandana Chakraborti, and Anindita Mondal, and Ujjal Pattyanayak, and Rajesh Kumar Agarwal, and Partha Tripathi
Spontaneous dislocation of a transparent lens to the anterior chamber--a case report.
January 2010, Srpski arhiv za celokupno lekarstvo,
Udayaditya Mukhopadhyaya, and Chandana Chakraborti, and Anindita Mondal, and Ujjal Pattyanayak, and Rajesh Kumar Agarwal, and Partha Tripathi
[Dislocation of the crystalline lens into the anterior chamber following couching: Case report].
November 2017, Journal francais d'ophtalmologie,
Udayaditya Mukhopadhyaya, and Chandana Chakraborti, and Anindita Mondal, and Ujjal Pattyanayak, and Rajesh Kumar Agarwal, and Partha Tripathi
Spontaneous posterior dislocation of an intraocular lens presenting as pupillary block glaucoma.
February 2003, Journal of cataract and refractive surgery,
Udayaditya Mukhopadhyaya, and Chandana Chakraborti, and Anindita Mondal, and Ujjal Pattyanayak, and Rajesh Kumar Agarwal, and Partha Tripathi
[Spontaneous luxation of the crystalline lens into the anterior chamber (a clinical case report)].
January 1992, Oftalmologia (Bucharest, Romania : 1990),
Udayaditya Mukhopadhyaya, and Chandana Chakraborti, and Anindita Mondal, and Ujjal Pattyanayak, and Rajesh Kumar Agarwal, and Partha Tripathi
Spontaneous bilateral anterior crystalline lens dislocation.
March 2021, Journal francais d'ophtalmologie,
Udayaditya Mukhopadhyaya, and Chandana Chakraborti, and Anindita Mondal, and Ujjal Pattyanayak, and Rajesh Kumar Agarwal, and Partha Tripathi
Intracapsular lens extraction for the treatment of pupillary block glaucoma associated with anterior subluxation of the crystalline lens.
January 2013, Case reports in ophthalmology,
Udayaditya Mukhopadhyaya, and Chandana Chakraborti, and Anindita Mondal, and Ujjal Pattyanayak, and Rajesh Kumar Agarwal, and Partha Tripathi
[Dislocation of the crystalline lens into the anterior chamber].
December 2018, Journal francais d'ophtalmologie,
Copied contents to your clipboard!