BIOMAT Database Logo BIOMAT Database Logo

Functional Histology of Salivary Gland Pleomorphic Adenoma: An Appraisal. 2015

Asterios Triantafyllou, and Lester D R Thompson, and Kenneth O Devaney, and Diana Bell, and Jennifer L Hunt, and Alessandra Rinaldo, and Vincent Vander Poorten, and Alfio Ferlito
Oral and Maxillofacial Pathology, School of Dentistry, University of Liverpool, Liverpool, UK.

The complex microstructure of salivary gland pleomorphic adenoma is examined in relation to function. Events related to secretion of macromolecules and absorption, responses to the altered microenvironment and controversies concerning epithelial-mesenchymal transition versus modified myoepithelial differentiation are explored. Their effects on tumor cell phenotypes and arrangements are emphasized. Heterotopic differentiation and attempts at organogenesis are also considered. The approach allows interpreting microstructure independently of histogenetic perceptions, envisaging the tumor cells as a continuum, endorsing luminal structures as the principal components, and defining pleomorphic adenoma as a benign epithelial tumour characterized by variable epithelial-mesenchymal transition, secretion/differentiation and metaplasia.

UI MeSH Term Description Entries
D008949 Adenoma, Pleomorphic A benign, slow-growing tumor, most commonly of the salivary gland, occurring as a small, painless, firm nodule, usually of the parotid gland, but also found in any major or accessory salivary gland anywhere in the oral cavity. It is most often seen in women in the fifth decade. Histologically, the tumor presents a variety of cells: cuboidal, columnar, and squamous cells, showing all forms of epithelial growth. (Dorland, 27th ed) Mixed Salivary Gland Tumor,Salivary Gland Tumor, Mixed,Syringoma, Chondroid,Adenomas, Pleomorphic,Chondroid Syringoma,Chondroid Syringomas,Pleomorphic Adenoma,Pleomorphic Adenomas,Syringomas, Chondroid
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012468 Salivary Gland Neoplasms Tumors or cancer of the SALIVARY GLANDS. Cancer of Salivary Gland,Non-Sebaceous Lymphadenomas,Salivary Gland Cancer,Salivary Gland Lymphadenomas,Sebaceous Lymphadenomas,Cancer of the Salivary Gland,Neoplasms, Salivary Gland,Cancer, Salivary Gland,Cancers, Salivary Gland,Gland Neoplasm, Salivary,Gland Neoplasms, Salivary,Lymphadenoma, Non-Sebaceous,Lymphadenoma, Salivary Gland,Lymphadenoma, Sebaceous,Lymphadenomas, Non-Sebaceous,Lymphadenomas, Salivary Gland,Lymphadenomas, Sebaceous,Neoplasm, Salivary Gland,Non Sebaceous Lymphadenomas,Non-Sebaceous Lymphadenoma,Salivary Gland Cancers,Salivary Gland Lymphadenoma,Salivary Gland Neoplasm,Sebaceous Lymphadenoma

Related Publications

Asterios Triantafyllou, and Lester D R Thompson, and Kenneth O Devaney, and Diana Bell, and Jennifer L Hunt, and Alessandra Rinaldo, and Vincent Vander Poorten, and Alfio Ferlito
Salivary gland pleomorphic adenoma.
February 2008, American journal of clinical oncology,
Asterios Triantafyllou, and Lester D R Thompson, and Kenneth O Devaney, and Diana Bell, and Jennifer L Hunt, and Alessandra Rinaldo, and Vincent Vander Poorten, and Alfio Ferlito
Pleomorphic adenoma of minor salivary gland.
January 1984, Ultrastructural pathology,
Asterios Triantafyllou, and Lester D R Thompson, and Kenneth O Devaney, and Diana Bell, and Jennifer L Hunt, and Alessandra Rinaldo, and Vincent Vander Poorten, and Alfio Ferlito
Pleomorphic adenoma of minor salivary gland.
July 1983, Ultrastructural pathology,
Asterios Triantafyllou, and Lester D R Thompson, and Kenneth O Devaney, and Diana Bell, and Jennifer L Hunt, and Alessandra Rinaldo, and Vincent Vander Poorten, and Alfio Ferlito
Pleomorphic Adenoma of Minor Salivary Gland.
April 2022, Journal of the College of Physicians and Surgeons--Pakistan : JCPSP,
Asterios Triantafyllou, and Lester D R Thompson, and Kenneth O Devaney, and Diana Bell, and Jennifer L Hunt, and Alessandra Rinaldo, and Vincent Vander Poorten, and Alfio Ferlito
[Crystalloids in salivary gland pleomorphic adenoma].
September 1994, Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology,
Asterios Triantafyllou, and Lester D R Thompson, and Kenneth O Devaney, and Diana Bell, and Jennifer L Hunt, and Alessandra Rinaldo, and Vincent Vander Poorten, and Alfio Ferlito
Suprasellar salivary gland-like pleomorphic adenoma.
January 2014, Indian journal of pathology & microbiology,
Asterios Triantafyllou, and Lester D R Thompson, and Kenneth O Devaney, and Diana Bell, and Jennifer L Hunt, and Alessandra Rinaldo, and Vincent Vander Poorten, and Alfio Ferlito
[Cytogenetic subtyping of salivary gland pleomorphic adenoma and carcinoma in pleomorphic adenoma].
March 1994, Nihon Jibiinkoka Gakkai kaiho,
Asterios Triantafyllou, and Lester D R Thompson, and Kenneth O Devaney, and Diana Bell, and Jennifer L Hunt, and Alessandra Rinaldo, and Vincent Vander Poorten, and Alfio Ferlito
Metastasizing pleomorphic adenoma of the salivary gland.
September 2008, Archives of pathology & laboratory medicine,
Asterios Triantafyllou, and Lester D R Thompson, and Kenneth O Devaney, and Diana Bell, and Jennifer L Hunt, and Alessandra Rinaldo, and Vincent Vander Poorten, and Alfio Ferlito
Metastasizing pleomorphic adenoma of the salivary gland.
November 1978, Cancer,
Asterios Triantafyllou, and Lester D R Thompson, and Kenneth O Devaney, and Diana Bell, and Jennifer L Hunt, and Alessandra Rinaldo, and Vincent Vander Poorten, and Alfio Ferlito
[Pleomorphic adenoma of the minor salivary gland].
January 1995, Acta otorrinolaringologica espanola,
Copied contents to your clipboard!