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OBJECTIVE Phthalates are environmental chemicals with reproductive toxicity and estrogenic effects in animals. They are of increasing concern to human health. OBJECTIVE To determine whether phthalate levels in semen were associated with infertility. METHODS Using semen samples from 107 infertile and 94 fertile men, the presence and quantity of five phthalate esters were measured using high-performance liquid chromatography (HPLC). Using data collected from questionnaires and clinical examinations, the correlation between phthalate exposure and semen quality was analyzed. RESULTS The cumulative levels of the measured phthalate esters were significantly higher in the infertility group compared to the control group (P<0ยท05). Concentrations of the five phthalate esters in men varied by age with older men showing higher cumulative levels. CONCLUSIONS The presence of phthalates may contribute to male infertility in our study population.
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Yong-Hui Wu
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Sheng-Yuan Wang, and
Yu Wang, and
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Yong-Hui Wu
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Sheng-Yuan Wang, and
Yu Wang, and
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Yong-Hui Wu
May 1982,
Archives of andrology,
Sheng-Yuan Wang, and
Yu Wang, and
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January 1989,
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Sheng-Yuan Wang, and
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Sheng-Yuan Wang, and
Yu Wang, and
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Sheng-Yuan Wang, and
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Sheng-Yuan Wang, and
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Yong-Hui Wu
January 1964,
Fertility and sterility,
Sheng-Yuan Wang, and
Yu Wang, and
Fang-Qin Xie, and
Yan-Xing Li, and
Xue-Lian Wan, and
Wei-Wei Ma, and
De-Cai Wang, and
Yong-Hui Wu
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Sheng-Yuan Wang, and
Yu Wang, and
Fang-Qin Xie, and
Yan-Xing Li, and
Xue-Lian Wan, and
Wei-Wei Ma, and
De-Cai Wang, and
Yong-Hui Wu
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