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Pneumocystis carinii is an opportunistic pathogen of man, carried as a commensal in healthy subjects. It frequently causes a fatal pneumonia in the immunosuppressed host. It is a major complication of HIV-1 infection in man (AIDS). Using surface radioiodination of rat-derived P. carinii trophozoites obtained from in vitro culture, a major surface glycoprotein (gp120) has been identified. The glycoprotein exhibits adherent behavior similar to that of the intact organism. Purification of gp120 by conventional methods was unsuccessful as the glycoprotein irreversibly bound to numerous column matrices. A combination of gel chromatography and hydroxyapatite chromatography in sodium dodecylsulfate was utilized to purify the glycoprotein. Some preliminary characterization of the glycoprotein is presented.
J A Radding, and
M Y Armstrong, and
M S Bogucki, and
F F Richards
January 1993,
The Journal of eukaryotic microbiology,
J A Radding, and
M Y Armstrong, and
M S Bogucki, and
F F Richards
January 1999,
The Journal of eukaryotic microbiology,
J A Radding, and
M Y Armstrong, and
M S Bogucki, and
F F Richards
September 1985,
Diagnostic microbiology and infectious disease,
J A Radding, and
M Y Armstrong, and
M S Bogucki, and
F F Richards
January 1989,
The Journal of protozoology,
J A Radding, and
M Y Armstrong, and
M S Bogucki, and
F F Richards
January 1989,
The Journal of protozoology,
J A Radding, and
M Y Armstrong, and
M S Bogucki, and
F F Richards
April 1977,
Pediatric research,
J A Radding, and
M Y Armstrong, and
M S Bogucki, and
F F Richards
April 1978,
Infection and immunity,
J A Radding, and
M Y Armstrong, and
M S Bogucki, and
F F Richards
January 1989,
The Journal of protozoology,
J A Radding, and
M Y Armstrong, and
M S Bogucki, and
F F Richards
September 1998,
FEMS immunology and medical microbiology,
J A Radding, and
M Y Armstrong, and
M S Bogucki, and
F F Richards
February 2001,
Infection and immunity,
