Biomaterial Database

[The frequency and pathogenesis of feline infectious peritonitis (FIP)]. 1989

J H Walter, and R Rudolph

Between 1980 and 1987 about 10% of the cats which underwent a post mortem examination at the Institute of Veterinary Pathology of the Freie Universität Berlin were infected with feline infectious peritonitis (FIP). The exudative, granulomatous or mixed form of the FIP are all symptoms of the same disease whose clinical picture is dependent on the state of the cellular immunity. Statistically there is no significant relationship between the form of the FIP and the age of the cats. A breed or a sex disposition is also not apparent. 42 organs and/or tissue samples were taken from a total of 30 cats and were examined both histologically and immunohistochemically. The antigen is located, above all, in the mesothelium and the cells of the mononuclear phagocyte system, whereas the parenchymatous inflammation foci show little evidence of the FIP-virus-antigen. The antigen is, however, also found in the nerve cells. Within the framework of a second viraemia, occurring after infection of the mesothelium (polyserositis), a perivasculitis non purulenta generalisata occurs. Possible excretory organs of the antigen are the respiratory, digestive and urinary tract.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D010538	Peritonitis	INFLAMMATION of the PERITONEUM lining the ABDOMINAL CAVITY as the result of infectious, autoimmune, or chemical processes. Primary peritonitis is due to infection of the PERITONEAL CAVITY via hematogenous or lymphatic spread and without intra-abdominal source. Secondary peritonitis arises from the ABDOMINAL CAVITY itself through RUPTURE or ABSCESS of intra-abdominal organs.	Primary Peritonitis,Secondary Peritonitis,Peritonitis, Primary,Peritonitis, Secondary
D002371	Cat Diseases	Diseases of the domestic cat (Felis catus or F. domesticus). This term does not include diseases of the so-called big cats such as CHEETAHS; LIONS; tigers, cougars, panthers, leopards, and other Felidae for which the heading CARNIVORA is used.	Feline Diseases,Cat Disease,Disease, Cat,Disease, Feline,Diseases, Cat,Diseases, Feline,Feline Disease
D002415	Cats	The domestic cat, Felis catus, of the carnivore family FELIDAE, comprising over 30 different breeds. The domestic cat is descended primarily from the wild cat of Africa and extreme southwestern Asia. Though probably present in towns in Palestine as long ago as 7000 years, actual domestication occurred in Egypt about 4000 years ago. (From Walker's Mammals of the World, 6th ed, p801)	Felis catus,Felis domesticus,Domestic Cats,Felis domestica,Felis sylvestris catus,Cat,Cat, Domestic,Cats, Domestic,Domestic Cat
D003333	Coronaviridae Infections	Virus diseases caused by CORONAVIRIDAE.	Infections, Coronaviridae,Coronaviridae Infection,Infection, Coronaviridae
D005260	Female		Females
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D012189	Retrospective Studies	Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.	Retrospective Study,Studies, Retrospective,Study, Retrospective