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A series of 41 poorly differentiated follicular carcinomas of the thyroid gland without histopathological features of medullary or papillary carcinoma and 9 cases of undifferentiated thyroid carcinoma of the small cell type (diagnosed between 1967 and 1983) were investigated immunohistochemically. Two poorly differentiated follicular carcinomas showed a considerable number of calcitonin-positive cells in addition to the weakly thyroglobulin-positive tumor cells. One of these cases revealed several areas with calcitonin-positive tumor cells with additional squamous metaplasia with keratinization. No medullary carcinomas could be demonstrated among the 9 cases previously diagnosed as undifferentiated thyroid carcinomas of the small cell type. From the epidemiological point of view the application of immunohistochemistry does not significantly increase the proportion of medullary carcinomas detected in our endemic goiter area. The incidence of medullary carcinoma remains surprisingly low when compared with nonendemic areas.
K W Schmid, and
M Tötsch, and
A Hittmair, and
H Feichtinger, and
D Ladurner, and
F Hofstädter
January 1966,
The American journal of medicine,
K W Schmid, and
M Tötsch, and
A Hittmair, and
H Feichtinger, and
D Ladurner, and
F Hofstädter
February 1955,
The New England journal of medicine,
K W Schmid, and
M Tötsch, and
A Hittmair, and
H Feichtinger, and
D Ladurner, and
F Hofstädter
January 2018,
Indian journal of endocrinology and metabolism,
K W Schmid, and
M Tötsch, and
A Hittmair, and
H Feichtinger, and
D Ladurner, and
F Hofstädter
April 1987,
The Surgical clinics of North America,
K W Schmid, and
M Tötsch, and
A Hittmair, and
H Feichtinger, and
D Ladurner, and
F Hofstädter
April 1980,
Klinische Wochenschrift,
K W Schmid, and
M Tötsch, and
A Hittmair, and
H Feichtinger, and
D Ladurner, and
F Hofstädter
January 2016,
Journal of thyroid research,
K W Schmid, and
M Tötsch, and
A Hittmair, and
H Feichtinger, and
D Ladurner, and
F Hofstädter
February 2001,
Journal of pediatric endocrinology & metabolism : JPEM,
K W Schmid, and
M Tötsch, and
A Hittmair, and
H Feichtinger, and
D Ladurner, and
F Hofstädter
August 1958,
Journal of the American Medical Association,
K W Schmid, and
M Tötsch, and
A Hittmair, and
H Feichtinger, and
D Ladurner, and
F Hofstädter
January 1968,
Archiv fur klinische Medizin,
K W Schmid, and
M Tötsch, and
A Hittmair, and
H Feichtinger, and
D Ladurner, and
F Hofstädter
September 1986,
The Journal of clinical endocrinology and metabolism,
