The regularity of smoked marijuana self-administration. 1989

R W Foltin, and M W Fischman, and J V Brady, and R M Capriotti, and C S Emurian
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21205.

Three male research volunteers lived in a residential laboratory for 12 days in a study designed to investigate factors controlling patterns of marijuana smoking. All contact with the experimenters was through a networked computer system and subjects' behaviors were continuously recorded. During the first six hr of the day (0945-1545), subjects remained in their private rooms engaging in planned work activities, and during the remainder of the day (7 3/4 hr) they were allowed to socialize (1600-2345). Subjects were instructed that up to five active marijuana cigarettes (1.84% delta 9 w/w THC) could be smoked on designated days between 0945 and 2200. Cigarettes were available on request. Subjects requested all five cigarettes on 15 of 18 possible occasions (three subjects x six days of availability) with a mean latency to the first cigarette of 22 min. The pattern of self-administration was remarkably similar among subjects with all subjects smoking two cigarettes during the private work period and three cigarettes during the social access period. Subjects 1 and 2 smoked 90% of their social period cigarettes together in the social area, while Subject 3 smoked all of his cigarettes alone in his private room.

UI MeSH Term Description Entries
D008297 Male Males
D008385 Marijuana Smoking Inhaling and exhaling SMOKE from CANNABIS. Cannabis Smoking,Hashish Smoking,Marihuana Smoking,Smoking Blunts,Smoking, Blunts,Blunt, Smoking,Blunts Smoking,Blunts Smokings,Blunts, Smoking,Smoking Blunt,Smoking, Cannabis,Smoking, Hashish,Smoking, Marihuana,Smoking, Marijuana,Smokings, Blunts
D002149 Energy Intake Total number of calories taken in daily whether ingested or by parenteral routes. Caloric Intake,Calorie Intake,Intake, Calorie,Intake, Energy
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D013759 Dronabinol A psychoactive compound extracted from the resin of Cannabis sativa (marihuana, hashish). The isomer delta-9-tetrahydrocannabinol (THC) is considered the most active form, producing characteristic mood and perceptual changes associated with this compound. THC,Tetrahydrocannabinol,delta(9)-THC,9-ene-Tetrahydrocannabinol,Marinol,Tetrahydrocannabinol, (6a-trans)-Isomer,Tetrahydrocannabinol, (6aR-cis)-Isomer,Tetrahydrocannabinol, (6aS-cis)-Isomer,Tetrahydrocannabinol, Trans-(+-)-Isomer,Tetrahydrocannabinol, Trans-Isomer,delta(1)-THC,delta(1)-Tetrahydrocannabinol,delta(9)-Tetrahydrocannabinol,9 ene Tetrahydrocannabinol,Tetrahydrocannabinol, Trans Isomer

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