OBJECTIVE To develop a method of gas chromatography (GC) for determining residues of promtryne in shellfish. METHODS The sample was extracted with ethyl acetate, and cleaned-up with Envi-Carb SPE cartridge, alumina-N SPE cartridge, and determined by GC-FPD with DB - 1701 capillary chromatographic column (30 m x0.53 .mm x 0.5µm). RESULTS Good linear was obtained in the concentration range of 0.10-0.96µg/ml with a correlation coefficient of 0. 999. The limit of detection (LOD) was 0.0037 mg/kg and limit of quantity (LOQ) was 0.010 mg/kg. The average recoveries was 83. 7% - 102. 0% and relative standard deviations (RSD) was 0. 54% - 8.14% CONCLUSIONS The method is simple, fast and credible, so it can be applied to determination of prometryne in shellfish.