Biomaterial Database

[Myeloperoxidase of neutrophils and its possible role in lipid peroxidation processes in arteriosclerosis]. 1989

E F Davidenkova, and M G Shafron

Activity of blood plasma myeloperoxidase (MPO) of neutrophil leucocytes and acetyl hydroperoxides was studied in families of atherosclerosis patients. The neutrophil MPO activity was decreased and the blood plasma content of acetyl hydroperoxides was increased in subjects with hereditary predisposition to atherosclerosis. The role of MPO and its possible pathogenetic action as a generator of the active forms of oxygen in atherosclerosis and its complications has been discussed.

UI	MeSH Term	Description	Entries
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D009195	Peroxidase	A hemeprotein from leukocytes. Deficiency of this enzyme leads to a hereditary disorder coupled with disseminated moniliasis. It catalyzes the conversion of a donor and peroxide to an oxidized donor and water. EC 1.11.1.7.	Myeloperoxidase,Hemi-Myeloperoxidase,Hemi Myeloperoxidase
D009504	Neutrophils	Granular leukocytes having a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes.	LE Cells,Leukocytes, Polymorphonuclear,Polymorphonuclear Leukocytes,Polymorphonuclear Neutrophils,Neutrophil Band Cells,Band Cell, Neutrophil,Cell, LE,LE Cell,Leukocyte, Polymorphonuclear,Neutrophil,Neutrophil Band Cell,Neutrophil, Polymorphonuclear,Polymorphonuclear Leukocyte,Polymorphonuclear Neutrophil
D010463	Peracetic Acid	A liquid that functions as a strong oxidizing agent. It has an acrid odor and is used as a disinfectant.	Acetyl Hydroperoxide,Peroxyacetic Acid,Desoxone-1,Dialax,Peracetic Acid, Sodium Salt,Peroxyethanoic Acid,Sodium Peracetate,Zinc Peracetate,Acid, Peracetic,Acid, Peroxyacetic,Acid, Peroxyethanoic,Desoxone 1,Desoxone1,Peracetate, Sodium,Peracetate, Zinc
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293	Adolescent	A person 13 to 18 years of age.	Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D000368	Aged	A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available.	Elderly
D001161	Arteriosclerosis	Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries.	Arterioscleroses
D015227	Lipid Peroxidation	Peroxidase catalyzed oxidation of lipids using hydrogen peroxide as an electron acceptor.	Lipid Peroxidations,Peroxidation, Lipid,Peroxidations, Lipid