-transparent.png){kind=logo}
We have established a new Epstein-Barr virus transformed cell line from a patient with B-cell follicular lymphoma. Telomeric fusions were observed in several subclones, with the nonrandom involvement of chromosomes 1, 5, 12, and 17. Centromeric staining with immunofluorescent anti-kinetochore antibodies was positive in both centromeres of the fused chromosomes, suggesting they were both active. Unlike previously reported cases, we were unable to demonstrate telomeric fusions directly in cells from the patient's blood. However, the finding of identical immunoglobulin gene rearrangements in DNA from the patient's blood and cell line suggested that they originated from the same malignant B-cell clone.
D Saltman, and
F M Ross, and
J A Fantes, and
R Allshire, and
G E Turner, and
H J Evans
January 1991,
Cytogenetics and cell genetics,
D Saltman, and
F M Ross, and
J A Fantes, and
R Allshire, and
G E Turner, and
H J Evans
June 1993,
Genes, chromosomes & cancer,
D Saltman, and
F M Ross, and
J A Fantes, and
R Allshire, and
G E Turner, and
H J Evans
August 2016,
Biochimica et biophysica acta,
D Saltman, and
F M Ross, and
J A Fantes, and
R Allshire, and
G E Turner, and
H J Evans
May 2021,
Cureus,
D Saltman, and
F M Ross, and
J A Fantes, and
R Allshire, and
G E Turner, and
H J Evans
November 2002,
Leukemia & lymphoma,
D Saltman, and
F M Ross, and
J A Fantes, and
R Allshire, and
G E Turner, and
H J Evans
January 2012,
PloS one,
D Saltman, and
F M Ross, and
J A Fantes, and
R Allshire, and
G E Turner, and
H J Evans
May 2023,
BMJ case reports,
D Saltman, and
F M Ross, and
J A Fantes, and
R Allshire, and
G E Turner, and
H J Evans
December 1985,
Cell biology international reports,
D Saltman, and
F M Ross, and
J A Fantes, and
R Allshire, and
G E Turner, and
H J Evans
June 1988,
Endocrinology,
D Saltman, and
F M Ross, and
J A Fantes, and
R Allshire, and
G E Turner, and
H J Evans
December 1980,
Cancer,
