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The authors give an account on the treatment and their own observations of the biological behaviour of verrucous carcinoma in five patients treated in the Radiotherapeutic Institute of the Municipal Institute of National Health and ENT Clinic of the Institute for Postgraduate Medical Training. They recommend in verrucous formations of the larynx bioptic examination and investigation of the presence of koilocytes. Koilocytes are generally considered a biological correlate of the presence of the HPV virus. At present the HUV virus, types 16, 18 and 30, are considered the possible aetiological agent of verrucous carcinoma. The method of choice in the treatment of verrucous carcinoma is surgery.
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