OBJECTIVE In this study we aim to assess the mortality of patients undergoing cardiac surgery and that in the post operative period required veno-venous hemofiltration. METHODS The population studied includes 77 patients (44 men and 33 women, with mean age 67,04±12.99 years), that underwent cardiac surgery between January 2008 and March 2013, requiring veno-venous hemofiltration after surgery. 3 surgeries were urgent, 3 emergent and the other elective, 18 of which were re operations. 31 patients underwent valvular surgery, 14 myocardial revascularization surgery, 8 patients combined valvular and myocardial revascularization surgery and 22 patients other surgery. The mean EuroScore I of the study group was 15,8% (maximum of 57 and minimum of 2.2%). The mean length of stay in the intensive care unit was 18 days (maximum of 185 days and minimum of 1 day). The mean length of hospital stay was 26 days (maximum of 190 days and minimum of 1 day). RESULTS The overall mortality of the study group was 40,3% (31 patients), the hospital mortality was 31,2%(24 patients) and mortality after discharge was 9,1% (7 patients). The mean EuroScore of patients undergoing cardiac surgery alone was 5,8% and the hospital mortality was 2,8%. Mortality after 1 year follow up was 6.1%. CONCLUSIONS Patients undergoing veno-venous hemofiltration have a much higher EuroScore and mortality rate when compared to the population undergoing cardiac surgery alone. We conclude that the mortality of patients undergoing cardiac surgery and that require hemofiltration after surgery is similar to the other published studies regarding this type of patient.