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To assess if a dehydrated extract of nopal stems retains the effect on glycemia of the entire nopal stems two experiments were performed. A. Six patients with type II diabetes mellitus in fasting condition received 30 capsules containing 10.1 +/- 0.3 g of the extract, and serum glucose levels were measured hourly from 0 to 180 minutes. B. Six healthy volunteers received 30 capsules with the extract followed by 74 g of dextrose orally. Serum glucose measurements were made in a similar fashion. In each experiment a control test with empty capsules was performed. Nopal extract did not reduce fasting glycemia in diabetic subjects. Nevertheless, the extract diminished the increase of serum glucose which followed a dextrose load. Peak serum glucose was 20.3 +/- 18.2 mg/dl (X +/- SD) lower in the test with nopal than in the control one (P less than 0.025). Dehydrated extract of nopal (Opuntia ficus-indica Mill) did not show acute hypoglycemic effect, although could attenuate postprandial hyperglycemia.
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C de León, and
R Ariza-Andraca, and
M B Bañales-Ham, and
R López-Ledesma, and
X Lozoya
January 2013,
Food & nutrition research,
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December 1998,
Archivos latinoamericanos de nutricion,
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May 2023,
Journal of functional biomaterials,
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M B Bañales-Ham, and
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December 2021,
Antioxidants (Basel, Switzerland),
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April 2007,
Phytotherapy research : PTR,
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September 2007,
Plant foods for human nutrition (Dordrecht, Netherlands),
A C Frati-Munari, and
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June 1969,
Bollettino della Societa italiana di biologia sperimentale,
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June 2001,
Journal of ethnopharmacology,
A C Frati-Munari, and
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M B Bañales-Ham, and
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X Lozoya
January 2022,
Current topics in medicinal chemistry,
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May 2022,
Wei sheng yan jiu = Journal of hygiene research,
