Biomaterial Database

[Papillary edema in Muckle-Wells syndrome]. 2015

G Wirths, and U Grenzebach, and N Eter

Universitätsaugenklinik Münster, Domagkstr. 15, 48149, Münster, Deutschland. Gabriele.wirths@ukmuenster.de.

Papillary edema may occur isolated without functional impairment or secondary related to various syndromes, increased intracerebral pressure or associated with medicinal treatment. The Muckle-Wells syndrome is a rare disease, which among many other symptoms can lead to optic disc swelling and recurrent increase in intracerebral pressure. Besides familial cold-induced autoinflammatory syndrome (FCAS) and neonatal onset multisystem inflammatory disease (NOMID), the Muckle-Wells syndrome also belongs to the cryopyrin-associated periodic syndromes (CAPS). In most cases of CAP syndromes there is an underlying genetic disorder that leads to overproduction of interleukin-1β (IL-1β); therefore, typical symptoms include inflammation reactions, such as repeated skin rash, fatigue, fever, joint pain and conjunctivitis.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D010211	Papilledema	Swelling of the OPTIC DISK, usually in association with increased intracranial pressure, characterized by hyperemia, blurring of the disk margins, microhemorrhages, blind spot enlargement, and engorgement of retinal veins. Chronic papilledema may cause OPTIC ATROPHY and visual loss. (Miller et al., Clinical Neuro-Ophthalmology, 4th ed, p175)	Choked Disk,Edema of the Optic Disc,Edema of the Optic Disk,Optic Disc Edema,Optic Disk Edema,Optic Papilla Edema,Papillitis, Optic,Decreased Intraocular Pressure-Associated Papilledema,Increased Intracranial Pressure-Associated Papilledema,Optic Nerve Papillitis,Papilledema Associated with Decreased Intraocular Pressure,Papilledema Associated with Increased Intracranial Pressure,Papillitis,Retinal Edema,Choked Disks,Decreased Intraocular Pressure Associated Papilledema,Disk, Choked,Edema, Optic Disc,Edema, Optic Disk,Edema, Optic Papilla,Edema, Retinal,Edemas, Optic Disc,Edemas, Optic Disk,Edemas, Retinal,Increased Intracranial Pressure Associated Papilledema,Optic Papillitis,Papillitis, Optic Nerve,Retinal Edemas
D002648	Child	A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL.	Children
D003937	Diagnosis, Differential	Determination of which one of two or more diseases or conditions a patient is suffering from by systematically comparing and contrasting results of diagnostic measures.	Diagnoses, Differential,Differential Diagnoses,Differential Diagnosis
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000893	Anti-Inflammatory Agents	Substances that reduce or suppress INFLAMMATION.	Anti-Inflammatory Agent,Antiinflammatory Agent,Agents, Anti-Inflammatory,Agents, Antiinflammatory,Anti-Inflammatories,Antiinflammatories,Antiinflammatory Agents,Agent, Anti-Inflammatory,Agent, Antiinflammatory,Agents, Anti Inflammatory,Anti Inflammatories,Anti Inflammatory Agent,Anti Inflammatory Agents
D016896	Treatment Outcome	Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.	Rehabilitation Outcome,Treatment Effectiveness,Clinical Effectiveness,Clinical Efficacy,Patient-Relevant Outcome,Treatment Efficacy,Effectiveness, Clinical,Effectiveness, Treatment,Efficacy, Clinical,Efficacy, Treatment,Outcome, Patient-Relevant,Outcome, Rehabilitation,Outcome, Treatment,Outcomes, Patient-Relevant,Patient Relevant Outcome,Patient-Relevant Outcomes
D056587	Cryopyrin-Associated Periodic Syndromes	A group of rare autosomal dominant diseases, commonly characterized by atypical URTICARIA (hives) with systemic symptoms that develop into end-organ damage. The atypical hives do not involve T-cell or autoantibody. Cryopyrin-associated periodic syndrome includes three previously distinct disorders: Familial cold autoinflammatory syndrome; Muckle-Wells Syndrome; and CINCA Syndrome, that are now considered to represent a disease continuum, all caused by NLRP3 PROTEIN mutations.	CINCA Syndrome,Chronic Infantile Neurological, Cutaneous, and Articular Syndrome,Cryopyrin Associated Periodic Syndrome,Cryopyrinopathy,Familial Cold Autoinflammatory Syndrome,Familial Cold Urticaria,IOMID,Infantile Onset Multisystem Inflammatory Disease,Muckle-Wells Syndrome,Multisystem Inflammatory Disease, Neonatal-Onset,NOMID,Neonatal Onset Multisystem Inflammatory Disease,CINCA,Chronic Infantile Neurologic, Cutaneous, and Articular Syndrome,Chronic Neurologic Cutaneous and Articular Syndrome,Chronic Neurologic, Cutaneous, and Articular Syndrome,Chronic, Infantile, Neurological, Cutaneous, Articular Syndrome,Cold Urticaria, Familial,Cold-Induced Autoinflammatory Syndrome, Familial,FCAS1,Familial Cold Autoinflammatory Syndrome 1,Familial Cold-Induced Autoinflammatory Syndrome,IOMID Syndrome,Prieur-Griscelli Syndrome,UDA Syndrome,Urticaria, Deafness and Amyloidosis,Urticaria-Deafness-Amyloidosis Syndrome,Cold Induced Autoinflammatory Syndrome, Familial,Cryopyrin Associated Periodic Syndromes,Cryopyrin-Associated Periodic Syndrome,Cryopyrinopathies,Familial Cold Induced Autoinflammatory Syndrome,Familial Cold Urticarias,IOMID Syndromes,Muckle Wells Syndrome,Multisystem Inflammatory Disease, Neonatal Onset,Prieur Griscelli Syndrome,Prieur-Griscelli Syndromes,Syndrome, IOMID,Syndrome, Muckle-Wells,Syndrome, Prieur-Griscelli,Syndrome, UDA,Syndrome, Urticaria-Deafness-Amyloidosis,UDA Syndromes,Urticaria Deafness Amyloidosis Syndrome,Urticaria, Familial Cold,Urticaria-Deafness-Amyloidosis Syndromes
D041623	Tomography, Optical Coherence	An imaging method using LASERS that is used for mapping subsurface structure. When a reflective site in the sample is at the same optical path length (coherence) as the reference mirror, the detector observes interference fringes.	OCT Tomography,Optical Coherence Tomography,Coherence Tomography, Optical,Tomography, OCT