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This report focuses on two groups of cationic cancerostatics, anthracycline antibiotics and 1,4-benzoquinone-guanylhydrazone-thiosemicarbazone (ambazone), lining up biophysical and biochemical effects on the level of membranes and membrane constituents. The interaction of both drugs with multilamellar liposomes consisting of phosphatidylcholine used as a simple model membrane system could be ensured by means of steady state and nanosecond time-resolved fluorometric investigations. The biochemical effect on membranes is underlined by the inhibition of the neuraminidase activity of the Sendai virus, modification of the CAMP phosphodiesterase activity of leukemia L 1210 cells of mice and reduction of the lymphocyte blast transformation.
G Löber, and
K Geller, and
H Hanschmann, and
L M Popa, and
R Repanovici, and
R Iliescu, and
W Römer, and
B Janke, and
V Kleinwächter
January 2020,
Mini reviews in medicinal chemistry,
G Löber, and
K Geller, and
H Hanschmann, and
L M Popa, and
R Repanovici, and
R Iliescu, and
W Römer, and
B Janke, and
V Kleinwächter
January 1977,
Advances in drug research,
G Löber, and
K Geller, and
H Hanschmann, and
L M Popa, and
R Repanovici, and
R Iliescu, and
W Römer, and
B Janke, and
V Kleinwächter
May 2009,
Deutsches Arzteblatt international,
G Löber, and
K Geller, and
H Hanschmann, and
L M Popa, and
R Repanovici, and
R Iliescu, and
W Römer, and
B Janke, and
V Kleinwächter
January 2021,
Best practice & research. Clinical gastroenterology,
G Löber, and
K Geller, and
H Hanschmann, and
L M Popa, and
R Repanovici, and
R Iliescu, and
W Römer, and
B Janke, and
V Kleinwächter
July 1997,
Veterinary journal (London, England : 1997),
G Löber, and
K Geller, and
H Hanschmann, and
L M Popa, and
R Repanovici, and
R Iliescu, and
W Römer, and
B Janke, and
V Kleinwächter
January 1986,
Basic life sciences,
G Löber, and
K Geller, and
H Hanschmann, and
L M Popa, and
R Repanovici, and
R Iliescu, and
W Römer, and
B Janke, and
V Kleinwächter
April 2021,
The Journal of organic chemistry,
G Löber, and
K Geller, and
H Hanschmann, and
L M Popa, and
R Repanovici, and
R Iliescu, and
W Römer, and
B Janke, and
V Kleinwächter
November 1985,
Proceedings of the National Academy of Sciences of the United States of America,
G Löber, and
K Geller, and
H Hanschmann, and
L M Popa, and
R Repanovici, and
R Iliescu, and
W Römer, and
B Janke, and
V Kleinwächter
January 2015,
Mini reviews in medicinal chemistry,
G Löber, and
K Geller, and
H Hanschmann, and
L M Popa, and
R Repanovici, and
R Iliescu, and
W Römer, and
B Janke, and
V Kleinwächter
January 1997,
Archivum immunologiae et therapiae experimentalis,
