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An epidemic of hemorrhagic fever with renal syndrome (HFRS) occurred in Yugoslavia May-November 1986; all Republics and Provinces were involved. Serum samples were received from 260 of 276 persons with symptoms clinically compatible with a diagnosis of HFRS. Presumptive infection with a hantavirus was determined serologically for 161 of these. Many patients with serious clinical pictures, including severe renal insufficiency and shock, were hospitalized; 11 died. Indirect fluorescent antibody tests with antigens of 4 hantaviruses (Hantaan, Fojnica, Puumala, and the Vranica strain of Puumala virus) showed that greater than 1 serotype was circulating during this epidemic. Hantavirus antigens were detected in the lungs of 86 of 302 (28.5%) wild-caught small mammals.
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M Obradović, and
R Stojanović, and
N Vujosević, and
A Ovcarić, and
M Frusic, and
C J Gibbs, and
C H Calisher, and
D C Gajdusek
May 1986,
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A Gligić, and
M Obradović, and
R Stojanović, and
N Vujosević, and
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M Frusic, and
C J Gibbs, and
C H Calisher, and
D C Gajdusek
April 1983,
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A Gligić, and
M Obradović, and
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D C Gajdusek
June 1962,
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A Gligić, and
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D C Gajdusek
December 1983,
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D C Gajdusek
December 1969,
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A Gligić, and
M Obradović, and
R Stojanović, and
N Vujosević, and
A Ovcarić, and
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C J Gibbs, and
C H Calisher, and
D C Gajdusek
January 1982,
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July 1992,
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A Ovcarić, and
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D C Gajdusek
April 1981,
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A Gligić, and
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D C Gajdusek
January 2003,
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M Obradović, and
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M Frusic, and
C J Gibbs, and
C H Calisher, and
D C Gajdusek
January 1988,
Zhonghua nei ke za zhi,
