Electromembrane Extraction of Organic Acid Compounds in Biological Samples Followed by High-Performance Liquid Chromatography. 2015

Mostafa Khajeh, and Mohammad Shakeri, and Zahra Bameri Natavan, and Zahra Safaei Moghaddam, and Mousa Bohlooli, and A A Moosavi-Movahedi
Department of Chemistry, University of Zabol, PO Box 98615-538, Zabol 98615-538, Iran m_khajeh@uoz.ac.ir.

Electromembrane extraction (EME) coupled with high-performance liquid chromatography was developed for determination of organic compounds including citric, tartaric and oxalic acid in biological samples. Organic compounds moved from aqueous samples, through a thin layer of 1-octanol immobilized in the pores of a porous hand-made polypropylene tube, and into a basic aqueous acceptor solution present inside the lumen of the tube. This new set-up for EME has a future potential such as simple, cheap and fast sample preparation technique for extraction of organic compounds in various complicated matrices. The pH of acceptor phase, extraction time, voltage, ionic strength, temperature and stirring speed were studied and optimized. Optimum conditions were: the pH of acceptor phase, 7; extraction time, 30 min; voltage, 30 V and stirring speed, 500 rpm. At the optimum conditions, the preconcentration factors of 175-200, the limits of detection of 1.9-3.1 µg L(-1) were obtained for the analytes. The developed procedure was then applied to the extraction and determination of organic acid compounds from biological samples.

UI MeSH Term Description Entries
D008567 Membranes, Artificial Artificially produced membranes, such as semipermeable membranes used in artificial kidney dialysis (RENAL DIALYSIS), monomolecular and bimolecular membranes used as models to simulate biological CELL MEMBRANES. These membranes are also used in the process of GUIDED TISSUE REGENERATION. Artificial Membranes,Artificial Membrane,Membrane, Artificial
D009930 Organic Chemicals A broad class of substances containing carbon and its derivatives. Many of these chemicals will frequently contain hydrogen with or without oxygen, nitrogen, sulfur, phosphorus, and other elements. They exist in either carbon chain or carbon ring form. Organic Chemical,Chemical, Organic,Chemicals, Organic
D002851 Chromatography, High Pressure Liquid Liquid chromatographic techniques which feature high inlet pressures, high sensitivity, and high speed. Chromatography, High Performance Liquid,Chromatography, High Speed Liquid,Chromatography, Liquid, High Pressure,HPLC,High Performance Liquid Chromatography,High-Performance Liquid Chromatography,UPLC,Ultra Performance Liquid Chromatography,Chromatography, High-Performance Liquid,High-Performance Liquid Chromatographies,Liquid Chromatography, High-Performance
D004867 Equipment Design Methods and patterns of fabricating machines and related hardware. Design, Equipment,Device Design,Medical Device Design,Design, Medical Device,Designs, Medical Device,Device Design, Medical,Device Designs, Medical,Medical Device Designs,Design, Device,Designs, Device,Designs, Equipment,Device Designs,Equipment Designs
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D013644 Tartrates Derivatives of tartronic acid (the structural formula (COOH)CHOH(COOH)) including its salts and esters.
D055664 Electrochemical Techniques The utilization of an electrical current to measure, analyze, or alter chemicals or chemical reactions in solution, cells, or tissues. Electrochemical Technics,Electrochemical Technic,Electrochemical Technique,Technic, Electrochemical,Technics, Electrochemical,Technique, Electrochemical,Techniques, Electrochemical
D057230 Limit of Detection Concentration or quantity that is derived from the smallest measure that can be detected with reasonable certainty for a given analytical procedure. Limits of Detection,Detection Limit,Detection Limits
D059627 Liquid Phase Microextraction Miniaturized methods of liquid-liquid extraction. Liquid-Liquid Microextraction,Micro Liquid Phase Extraction,Micro Liquid-Liquid Extraction,Extraction, Micro Liquid-Liquid,Extractions, Micro Liquid-Liquid,Liquid Liquid Microextraction,Liquid Phase Microextractions,Liquid-Liquid Extraction, Micro,Liquid-Liquid Extractions, Micro,Liquid-Liquid Microextractions,Micro Liquid Liquid Extraction,Micro Liquid-Liquid Extractions,Microextraction, Liquid Phase,Microextraction, Liquid-Liquid,Microextractions, Liquid Phase,Microextractions, Liquid-Liquid,Phase Microextraction, Liquid,Phase Microextractions, Liquid
D019343 Citric Acid A key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium chelating ability. Citrate,Anhydrous Citric Acid,Citric Acid Monohydrate,Citric Acid, Anhydrous,Uralyt U

Related Publications

Mostafa Khajeh, and Mohammad Shakeri, and Zahra Bameri Natavan, and Zahra Safaei Moghaddam, and Mousa Bohlooli, and A A Moosavi-Movahedi
July 2013, Analytica chimica acta,
Mostafa Khajeh, and Mohammad Shakeri, and Zahra Bameri Natavan, and Zahra Safaei Moghaddam, and Mousa Bohlooli, and A A Moosavi-Movahedi
September 2011, Analytica chimica acta,
Mostafa Khajeh, and Mohammad Shakeri, and Zahra Bameri Natavan, and Zahra Safaei Moghaddam, and Mousa Bohlooli, and A A Moosavi-Movahedi
June 2018, Journal of chromatography. A,
Mostafa Khajeh, and Mohammad Shakeri, and Zahra Bameri Natavan, and Zahra Safaei Moghaddam, and Mousa Bohlooli, and A A Moosavi-Movahedi
May 1982, Journal of chromatography,
Mostafa Khajeh, and Mohammad Shakeri, and Zahra Bameri Natavan, and Zahra Safaei Moghaddam, and Mousa Bohlooli, and A A Moosavi-Movahedi
November 2017, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences,
Mostafa Khajeh, and Mohammad Shakeri, and Zahra Bameri Natavan, and Zahra Safaei Moghaddam, and Mousa Bohlooli, and A A Moosavi-Movahedi
October 2006, Journal of chromatography. A,
Mostafa Khajeh, and Mohammad Shakeri, and Zahra Bameri Natavan, and Zahra Safaei Moghaddam, and Mousa Bohlooli, and A A Moosavi-Movahedi
August 1985, Analytical biochemistry,
Mostafa Khajeh, and Mohammad Shakeri, and Zahra Bameri Natavan, and Zahra Safaei Moghaddam, and Mousa Bohlooli, and A A Moosavi-Movahedi
November 2021, Journal of molecular recognition : JMR,
Mostafa Khajeh, and Mohammad Shakeri, and Zahra Bameri Natavan, and Zahra Safaei Moghaddam, and Mousa Bohlooli, and A A Moosavi-Movahedi
March 2006, Journal of chromatography. A,
Mostafa Khajeh, and Mohammad Shakeri, and Zahra Bameri Natavan, and Zahra Safaei Moghaddam, and Mousa Bohlooli, and A A Moosavi-Movahedi
June 2000, Methods and findings in experimental and clinical pharmacology,
Copied contents to your clipboard!