BIOMAT Database Logo BIOMAT Database Logo

Panuveitis caused by Borrelia burgdorferi sensu lato infection. 2015

Jasna Mahne, and Branka Stirn Kranjc, and Franc Strle, and Eva Ružić-Sabljić, and Maja Arnež
From the *Department of Infectious Diseases, University Medical Centre Ljubljana, Japljeva 2, 1525 Ljubljana; †Department of Ophthalmology, University Medical Centre Ljubljana, Grablovičeva 46; and ‡Institute of Microbiology and Immunology, School of Medicine, Zaloška 4, 1000 Ljubljana, Slovenia.

A 13-year-old boy who presented with a red left eye, painful eye movement, blurred vision, photophobia and increased lacrimation, was diagnosed with 1-sided panuveitis with optic disk edema. Diagnostic work-up revealed borrelial antibodies in serum. Diagnosis of Lyme borreliosis was substantiated by demonstration of lymphocytic pleocytosis, intrathecal borrelial antibody synthesis, improvement after treatment with ceftriaxone and exclusion of other causes.

UI MeSH Term Description Entries
D008193 Lyme Disease An infectious disease caused by a spirochete, BORRELIA BURGDORFERI, which is transmitted chiefly by Ixodes dammini (see IXODES) and pacificus ticks in the United States and Ixodes ricinis (see IXODES) in Europe. It is a disease with early and late cutaneous manifestations plus involvement of the nervous system, heart, eye, and joints in variable combinations. The disease was formerly known as Lyme arthritis and first discovered at Old Lyme, Connecticut. Lyme Borreliosis,B. burgdorferi Infection,Borrelia burgdorferi Infection,Lyme Arthritis,Arthritis, Lyme,B. burgdorferi Infections,Borrelia burgdorferi Infections,Borreliosis, Lyme,Disease, Lyme
D008218 Lymphocytosis Excess of normal lymphocytes in the blood or in any effusion. Lymphocytoses
D008297 Male Males
D002443 Ceftriaxone A broad-spectrum cephalosporin antibiotic and cefotaxime derivative with a very long half-life and high penetrability to meninges, eyes and inner ears. Benaxona,Cefatriaxone,Cefaxona,Ceftrex,Ceftriaxon,Ceftriaxon Curamed,Ceftriaxon Hexal,Ceftriaxona Andreu,Ceftriaxona LDP Torlan,Ceftriaxone Irex,Ceftriaxone Sodium,Ceftriaxone Sodium, Anhydrous,Ceftriaxone, Disodium Salt,Ceftriaxone, Disodium Salt, Hemiheptahydrate,Lendacin,Longacef,Longaceph,Ro 13-9904,Ro-13-9904,Ro13-9904,Rocefalin,Rocefin,Rocephin,Rocephine,Tacex,Terbac,Anhydrous Ceftriaxone Sodium,Ro 13 9904,Ro 139904,Ro13 9904,Ro139904
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D000900 Anti-Bacterial Agents Substances that inhibit the growth or reproduction of BACTERIA. Anti-Bacterial Agent,Anti-Bacterial Compound,Anti-Mycobacterial Agent,Antibacterial Agent,Antibiotics,Antimycobacterial Agent,Bacteriocidal Agent,Bacteriocide,Anti-Bacterial Compounds,Anti-Mycobacterial Agents,Antibacterial Agents,Antibiotic,Antimycobacterial Agents,Bacteriocidal Agents,Bacteriocides,Agent, Anti-Bacterial,Agent, Anti-Mycobacterial,Agent, Antibacterial,Agent, Antimycobacterial,Agent, Bacteriocidal,Agents, Anti-Bacterial,Agents, Anti-Mycobacterial,Agents, Antibacterial,Agents, Antimycobacterial,Agents, Bacteriocidal,Anti Bacterial Agent,Anti Bacterial Agents,Anti Bacterial Compound,Anti Bacterial Compounds,Anti Mycobacterial Agent,Anti Mycobacterial Agents,Compound, Anti-Bacterial,Compounds, Anti-Bacterial
D000907 Antibodies, Bacterial Immunoglobulins produced in a response to BACTERIAL ANTIGENS. Bacterial Antibodies
D015748 Borrelia burgdorferi Group Gram-negative helical bacteria, in the genus BORRELIA, that are the etiologic agents of LYME DISEASE. The group comprises many specific species including Borrelia afzelii, Borellia garinii, and BORRELIA BURGDORFERI proper. These spirochetes are generally transmitted by several species of ixodid ticks. Borrelia afzelii,Borrelia burgdorferi sensu lato,Borrelia garinii,Borreliella afzelii,Borreliella garinii
D015864 Panuveitis Inflammation in which both the anterior and posterior segments of the uvea are involved and a specific focus is not apparent. It is often severe and extensive and a serious threat to vision. Causes include systemic diseases such as tuberculosis, sarcoidosis, and syphilis, as well as malignancies. The intermediate segment of the eye is not involved.

Related Publications

Jasna Mahne, and Branka Stirn Kranjc, and Franc Strle, and Eva Ružić-Sabljić, and Maja Arnež
Treatment of infection caused by Borrelia burgdorferi sensu lato.
February 2011, Expert review of anti-infective therapy,
Jasna Mahne, and Branka Stirn Kranjc, and Franc Strle, and Eva Ružić-Sabljić, and Maja Arnež
Biofilm formation by Borrelia burgdorferi sensu lato.
August 2015, FEMS microbiology letters,
Jasna Mahne, and Branka Stirn Kranjc, and Franc Strle, and Eva Ružić-Sabljić, and Maja Arnež
Borrelia burgdorferi sensu lato infection in mosquitoes from Szczecin area.
January 2006, Folia biologica,
Jasna Mahne, and Branka Stirn Kranjc, and Franc Strle, and Eva Ružić-Sabljić, and Maja Arnež
Enzyme activities of Borrelia burgdorferi sensu lato.
January 2001, Folia microbiologica,
Jasna Mahne, and Branka Stirn Kranjc, and Franc Strle, and Eva Ružić-Sabljić, and Maja Arnež
Natural history of Borrelia burgdorferi sensu lato.
December 1998, Wiener klinische Wochenschrift,
Jasna Mahne, and Branka Stirn Kranjc, and Franc Strle, and Eva Ružić-Sabljić, and Maja Arnež
Molecular diagnosis of a bilateral panuveitis due to Borrelia burgdorferi sensu lato by cerebral spinal fluid analysis.
May 2008, Japanese journal of infectious diseases,
Jasna Mahne, and Branka Stirn Kranjc, and Franc Strle, and Eva Ružić-Sabljić, and Maja Arnež
Borrelia burgdorferi sensu lato infection in patients with peripheral facial palsy.
February 2019, Ticks and tick-borne diseases,
Jasna Mahne, and Branka Stirn Kranjc, and Franc Strle, and Eva Ružić-Sabljić, and Maja Arnež
Specificity of infection-induced immunity among Borrelia burgdorferi sensu lato species.
January 1999, Infection and immunity,
Jasna Mahne, and Branka Stirn Kranjc, and Franc Strle, and Eva Ružić-Sabljić, and Maja Arnež
Possible role of Borrelia burgdorferi sensu lato infection in lichen sclerosus.
May 2008, Archives of dermatology,
Jasna Mahne, and Branka Stirn Kranjc, and Franc Strle, and Eva Ružić-Sabljić, and Maja Arnež
European reservoir hosts of Borrelia burgdorferi sensu lato.
March 1998, Zentralblatt fur Bakteriologie : international journal of medical microbiology,
Copied contents to your clipboard!