BIOMAT Database Logo BIOMAT Database Logo

Explicit memory creation during sleep demonstrates a causal role of place cells in navigation. 2015

Gaetan de Lavilléon, and Marie Masako Lacroix, and Laure Rondi-Reig, and Karim Benchenane
1] Team Memory, Oscillations and Brain States (MOBs), Brain Plasticity Unit, CNRS UMR 8249, Ecole Supérieure de Physique et de Chimie Industrielles de la Ville de Paris, Paris, France. [2] Neuroscience Paris Seine, Cerebellum, Navigation and Memory Team, CNRS UMR 8246; INSERM, UMR-S 1130; Sorbonne Universités, University Pierre and Marie Curie, Paris, France.

Hippocampal place cells assemblies are believed to support the cognitive map, and their reactivations during sleep are thought to be involved in spatial memory consolidation. By triggering intracranial rewarding stimulations by place cell spikes during sleep, we induced an explicit memory trace, leading to a goal-directed behavior toward the place field. This demonstrates that place cells' activity during sleep still conveys relevant spatial information and that this activity is functionally significant for navigation.

UI MeSH Term Description Entries
D008297 Male Males
D008474 Medial Forebrain Bundle A complex group of fibers arising from the basal olfactory regions, the periamygdaloid region, and the septal nuclei, and passing to the lateral hypothalamus. Some fibers continue into the tegmentum. Median Forebrain Bundle,Bundle, Medial Forebrain,Bundle, Median Forebrain,Bundles, Medial Forebrain,Bundles, Median Forebrain,Forebrain Bundle, Medial,Forebrain Bundle, Median,Forebrain Bundles, Medial,Forebrain Bundles, Median,Medial Forebrain Bundles,Median Forebrain Bundles
D008810 Mice, Inbred C57BL One of the first INBRED MOUSE STRAINS to be sequenced. This strain is commonly used as genetic background for transgenic mouse models. Refractory to many tumors, this strain is also preferred model for studying role of genetic variations in development of diseases. Mice, C57BL,Mouse, C57BL,Mouse, Inbred C57BL,C57BL Mice,C57BL Mice, Inbred,C57BL Mouse,C57BL Mouse, Inbred,Inbred C57BL Mice,Inbred C57BL Mouse
D004558 Electric Stimulation Use of electric potential or currents to elicit biological responses. Stimulation, Electric,Electrical Stimulation,Electric Stimulations,Electrical Stimulations,Stimulation, Electrical,Stimulations, Electric,Stimulations, Electrical
D004567 Electrodes, Implanted Surgically placed electric conductors through which ELECTRIC STIMULATION is delivered to or electrical activity is recorded from a specific point inside the body. Implantable Electrodes,Implantable Stimulation Electrodes,Implanted Electrodes,Implanted Stimulation Electrodes,Electrode, Implantable,Electrode, Implantable Stimulation,Electrode, Implanted,Electrode, Implanted Stimulation,Electrodes, Implantable,Electrodes, Implantable Stimulation,Electrodes, Implanted Stimulation,Implantable Electrode,Implantable Stimulation Electrode,Implanted Electrode,Implanted Stimulation Electrode,Stimulation Electrode, Implantable,Stimulation Electrode, Implanted,Stimulation Electrodes, Implantable,Stimulation Electrodes, Implanted
D006040 Goals The end-result or objective, which may be specified or required in advance. Goal
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D001522 Behavior, Animal The observable response an animal makes to any situation. Autotomy Animal,Animal Behavior,Animal Behaviors
D012201 Reward An object or a situation that can serve to reinforce a response, to satisfy a motive, or to afford pleasure. Rewards

Related Publications

Gaetan de Lavilléon, and Marie Masako Lacroix, and Laure Rondi-Reig, and Karim Benchenane
Honeybees consolidate navigation memory during sleep.
November 2012, The Journal of experimental biology,
Gaetan de Lavilléon, and Marie Masako Lacroix, and Laure Rondi-Reig, and Karim Benchenane
Awareness in memory: being explicit about the role of sleep.
June 2004, Trends in cognitive sciences,
Gaetan de Lavilléon, and Marie Masako Lacroix, and Laure Rondi-Reig, and Karim Benchenane
Place cells and place navigation.
January 1997, Proceedings of the National Academy of Sciences of the United States of America,
Gaetan de Lavilléon, and Marie Masako Lacroix, and Laure Rondi-Reig, and Karim Benchenane
Implicit learning -- explicit knowing: a role for sleep in memory system interaction.
March 2006, Journal of cognitive neuroscience,
Gaetan de Lavilléon, and Marie Masako Lacroix, and Laure Rondi-Reig, and Karim Benchenane
Intracellular dynamics of hippocampal place cells during virtual navigation.
October 2009, Nature,
Gaetan de Lavilléon, and Marie Masako Lacroix, and Laure Rondi-Reig, and Karim Benchenane
Sleep enhances explicit recollection in recognition memory.
January 2005, Learning & memory (Cold Spring Harbor, N.Y.),
Gaetan de Lavilléon, and Marie Masako Lacroix, and Laure Rondi-Reig, and Karim Benchenane
A Visual-Cue-Dependent Memory Circuit for Place Navigation.
July 2018, Neuron,
Gaetan de Lavilléon, and Marie Masako Lacroix, and Laure Rondi-Reig, and Karim Benchenane
Closed-Loop Targeted Memory Reactivation during Sleep Improves Spatial Navigation.
January 2018, Frontiers in human neuroscience,
Gaetan de Lavilléon, and Marie Masako Lacroix, and Laure Rondi-Reig, and Karim Benchenane
Slow wave and REM sleep deprivation effects on explicit and implicit memory during sleep.
November 2016, Neuropsychology,
Gaetan de Lavilléon, and Marie Masako Lacroix, and Laure Rondi-Reig, and Karim Benchenane
The role of attention during encoding in implicit and explicit memory.
January 1998, Journal of experimental psychology. Learning, memory, and cognition,
Copied contents to your clipboard!