Biomaterial Database

TopBP1 stabilizes BLM protein to suppress sister chromatid exchange. 2015

Jiadong Wang, and Junjie Chen, and Zihua Gong

Institute of Systems Biomedicine, Department of Radiation Medicine, School of Basic Medical Sciences, Peking University, 38 Xueyuan Road, Beijing 100191, P.R. China.

UI	MeSH Term	Description	Entries
D009687	Nuclear Proteins	Proteins found in the nucleus of a cell. Do not confuse with NUCLEOPROTEINS which are proteins conjugated with nucleic acids, that are not necessarily present in the nucleus.	Nucleolar Protein,Nucleolar Proteins,Nuclear Protein,Protein, Nuclear,Protein, Nucleolar,Proteins, Nuclear,Proteins, Nucleolar
D002352	Carrier Proteins	Proteins that bind or transport specific substances in the blood, within the cell, or across cell membranes.	Binding Proteins,Carrier Protein,Transport Protein,Transport Proteins,Binding Protein,Protein, Carrier,Proteins, Carrier
D004268	DNA-Binding Proteins	Proteins which bind to DNA. The family includes proteins which bind to both double- and single-stranded DNA and also includes specific DNA binding proteins in serum which can be used as markers for malignant diseases.	DNA Helix Destabilizing Proteins,DNA-Binding Protein,Single-Stranded DNA Binding Proteins,DNA Binding Protein,DNA Single-Stranded Binding Protein,SS DNA BP,Single-Stranded DNA-Binding Protein,Binding Protein, DNA,DNA Binding Proteins,DNA Single Stranded Binding Protein,DNA-Binding Protein, Single-Stranded,Protein, DNA-Binding,Single Stranded DNA Binding Protein,Single Stranded DNA Binding Proteins
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D042822	Genomic Instability	An increased tendency of the GENOME to acquire MUTATIONS when various processes involved in maintaining and replicating the genome are dysfunctional.	Genome Instability,Genome Stability,Genomic Stability,Genome Instabilities,Genome Stabilities,Genomic Instabilities,Genomic Stabilities,Instabilities, Genome,Instabilities, Genomic,Instability, Genome,Instability, Genomic,Stabilities, Genome,Stabilities, Genomic,Stability, Genome,Stability, Genomic
D053484	RecQ Helicases	A family of structurally-related DNA helicases that play an essential role in the maintenance of genome integrity. RecQ helicases were originally discovered in E COLI and are highly conserved across both prokaryotic and eukaryotic organisms. Genetic mutations that result in loss of RecQ helicase activity gives rise to disorders that are associated with CANCER predisposition and premature aging.	RecQ Family of DNA Helicase,RecQ Helicase,ATP-Dependent DNA Helicase Q1,ATP-Dependent DNA Helicase Q4,ATP-Dependent DNA Helicase Q5,DNA Helicase Q1,DNA Helicase RecQL,DNA Helicase RecQL4,DNA Helicase, RecQ-like type 2,DNA-Dependent ATPase Q1,RECQL1 Helicase,RTS Helicase,RecQ Family of DNA Helicases,RecQ Protein,RecQ2 Helicase,RecQ3 Helicase,RecQ4 Helicase,RecQ5 Helicase,RecQ5L Helicase,RecQL Helicase,RecQL2 Helicase,RecQL3 Helicase,RecQL4 Helicase,ATP Dependent DNA Helicase Q1,ATP Dependent DNA Helicase Q4,ATP Dependent DNA Helicase Q5,DNA Dependent ATPase Q1,DNA Helicase, RecQ like type 2,Helicase, RECQL1,Helicase, RTS,Helicase, RecQ,Helicase, RecQ2,Helicase, RecQ3,Helicase, RecQ5,Helicase, RecQ5L,Helicase, RecQL,Helicase, RecQL2,Helicase, RecQL3,Helicase, RecQL4,Helicases, RecQ