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In 28 patients with non-seminomatous testicle tumour the tumour markers human chorionic gonadotropin (HCG) and alpha-fetoprotein (AFP) were determined radioimmunologically and enzymeimmunologically, respectively. While tumours with chorionic carcinoma (n = 8) always were marker-positive, in the embryonic carcinoma in 2 out of 10 cases falsely negative findings appeared. On 5 patients the biochemical monitoring of the course of the testicle tumour disease is demonstrated in detail by means of HCG and AFP and estimated as very helpful method. Advantages and problems of the marker diagnostics are shown and discussed. The positive marker findings were absolutely evident for a metastasation. On the other hand, marker negativation was not always to be equated with absence of a tumour and demanded a further control of the patient by means of all other available methods of diagnostics up to the second-look-operation.
C Boewer, and
S Nawka, and
H Fleck, and
M Uibel, and
U Immer, and
H E Schmidt, and
H Herzmann, and
G Pilgrim, and
R Ziegenbein
September 1980,
The Journal of urology,
C Boewer, and
S Nawka, and
H Fleck, and
M Uibel, and
U Immer, and
H E Schmidt, and
H Herzmann, and
G Pilgrim, and
R Ziegenbein
May 1983,
Acta pathologica, microbiologica, et immunologica Scandinavica. Section A, Pathology,
C Boewer, and
S Nawka, and
H Fleck, and
M Uibel, and
U Immer, and
H E Schmidt, and
H Herzmann, and
G Pilgrim, and
R Ziegenbein
January 2002,
The International journal of biological markers,
C Boewer, and
S Nawka, and
H Fleck, and
M Uibel, and
U Immer, and
H E Schmidt, and
H Herzmann, and
G Pilgrim, and
R Ziegenbein
December 1978,
Cancer,
C Boewer, and
S Nawka, and
H Fleck, and
M Uibel, and
U Immer, and
H E Schmidt, and
H Herzmann, and
G Pilgrim, and
R Ziegenbein
March 1984,
Nihon Hinyokika Gakkai zasshi. The japanese journal of urology,
C Boewer, and
S Nawka, and
H Fleck, and
M Uibel, and
U Immer, and
H E Schmidt, and
H Herzmann, and
G Pilgrim, and
R Ziegenbein
November 1975,
Minnesota medicine,
C Boewer, and
S Nawka, and
H Fleck, and
M Uibel, and
U Immer, and
H E Schmidt, and
H Herzmann, and
G Pilgrim, and
R Ziegenbein
October 1977,
The Journal of urology,
C Boewer, and
S Nawka, and
H Fleck, and
M Uibel, and
U Immer, and
H E Schmidt, and
H Herzmann, and
G Pilgrim, and
R Ziegenbein
January 1988,
International urology and nephrology,
C Boewer, and
S Nawka, and
H Fleck, and
M Uibel, and
U Immer, and
H E Schmidt, and
H Herzmann, and
G Pilgrim, and
R Ziegenbein
April 1983,
American journal of clinical pathology,
C Boewer, and
S Nawka, and
H Fleck, and
M Uibel, and
U Immer, and
H E Schmidt, and
H Herzmann, and
G Pilgrim, and
R Ziegenbein
January 1977,
Acta obstetricia et gynecologica Scandinavica. Supplement,
