Longitudinal associations between depression, anxiety, pain, and pain-related disability in chronic pain patients. 2015

Sheera F Lerman, and Zvia Rudich, and Silviu Brill, and Hadar Shalev, and Golan Shahar
From the Department of Psychology (Lerman, Shahar), Ben-Gurion University of the Negev, Beer-Sheva, Israel; Pain Specialty Clinic (Rudich, Shalev), Soroka University Medical Center, Beer-Sheva, Israel; Chaim Sheba Medical Center (Lerman), Tel Hashomer, Israel; and Pain Specialty Clinic (Brill), Sourasky Medical Center, Tel-Aviv, Israel.

OBJECTIVE The current study sets out to examine the longitudinal relationship between pain, pain-related disability, and symptoms of depression and anxiety. The latter symptoms are highly prevalent in chronic pain and seriously impede functioning and quality of life. Nevertheless, the direction of the relationship involving these variables among individuals with chronic pain is still unclear. METHODS Four-hundred twenty-eight individuals with chronic pain (238 women, mean age 54.84 years, mean pain duration 85.21 months) treated at two pain clinics completed questionnaires regarding their pain (Short-Form McGill Pain Questionnaire), depression (Center for Epidemiological Studies-Depression Scale), state anxiety (State-Trait Anxiety Inventory), and pain-related disability (Pain Disability Index) at four time points, with an average of 5 months between measurements. Cross-lagged, structural equation modeling analyses were performed, enabling the examination of longitudinal associations between the variables. RESULTS Significant symptoms of both depression and anxiety were reported by more than half of the sample on all waves. A latent depression/anxiety variable longitudinally predicted pain (β = .27, p < .001) and pain-related disability (β = .38, p < .001). However, neither pain (β = .10, p = .126) nor pain-related disability (β = -.01, p = .790) predicted depression/anxiety. CONCLUSIONS Among adult patients with chronic pain treated at specialty pain clinics, high levels of depression and anxiety may worsen pain and pain-related disability.

UI MeSH Term Description Entries
D008137 Longitudinal Studies Studies in which variables relating to an individual or group of individuals are assessed over a period of time. Bogalusa Heart Study,California Teachers Study,Framingham Heart Study,Jackson Heart Study,Longitudinal Survey,Tuskegee Syphilis Study,Bogalusa Heart Studies,California Teachers Studies,Framingham Heart Studies,Heart Studies, Bogalusa,Heart Studies, Framingham,Heart Studies, Jackson,Heart Study, Bogalusa,Heart Study, Framingham,Heart Study, Jackson,Jackson Heart Studies,Longitudinal Study,Longitudinal Surveys,Studies, Bogalusa Heart,Studies, California Teachers,Studies, Jackson Heart,Studies, Longitudinal,Study, Bogalusa Heart,Study, California Teachers,Study, Longitudinal,Survey, Longitudinal,Surveys, Longitudinal,Syphilis Studies, Tuskegee,Syphilis Study, Tuskegee,Teachers Studies, California,Teachers Study, California,Tuskegee Syphilis Studies
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D010147 Pain Measurement Scales, questionnaires, tests, and other methods used to assess pain severity and duration in patients or experimental animals to aid in diagnosis, therapy, and physiological studies. Analgesia Tests,Analogue Pain Scale,Formalin Test,McGill Pain Questionnaire,Nociception Tests,Pain Assessment,Pain Intensity,Pain Severity,Tourniquet Pain Test,Visual Analogue Pain Scale,Analog Pain Scale,Assessment, Pain,McGill Pain Scale,Visual Analog Pain Scale,Analgesia Test,Analog Pain Scales,Analogue Pain Scales,Formalin Tests,Intensity, Pain,Measurement, Pain,Nociception Test,Pain Assessments,Pain Intensities,Pain Measurements,Pain Questionnaire, McGill,Pain Scale, Analog,Pain Scale, Analogue,Pain Scale, McGill,Pain Severities,Pain Test, Tourniquet,Questionnaire, McGill Pain,Scale, Analog Pain,Scale, Analogue Pain,Scale, McGill Pain,Severity, Pain,Test, Analgesia,Test, Formalin,Test, Nociception,Test, Tourniquet Pain,Tests, Nociception,Tourniquet Pain Tests
D011446 Prospective Studies Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group. Prospective Study,Studies, Prospective,Study, Prospective
D011788 Quality of Life A generic concept reflecting concern with the modification and enhancement of life attributes, e.g., physical, political, moral, social environment as well as health and disease. HRQOL,Health-Related Quality Of Life,Life Quality,Health Related Quality Of Life
D011795 Surveys and Questionnaires Collections of data obtained from voluntary subjects. The information usually takes the form of answers to questions, or suggestions. Community Survey,Nonrespondent,Questionnaire,Questionnaires,Respondent,Survey,Survey Method,Survey Methods,Surveys,Baseline Survey,Community Surveys,Methodology, Survey,Nonrespondents,Questionnaire Design,Randomized Response Technique,Repeated Rounds of Survey,Respondents,Survey Methodology,Baseline Surveys,Design, Questionnaire,Designs, Questionnaire,Methods, Survey,Questionnaire Designs,Questionnaires and Surveys,Randomized Response Techniques,Response Technique, Randomized,Response Techniques, Randomized,Survey, Baseline,Survey, Community,Surveys, Baseline,Surveys, Community,Techniques, Randomized Response
D003863 Depression Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders. Depressive Symptoms,Emotional Depression,Depression, Emotional,Depressive Symptom,Symptom, Depressive
D004185 Disability Evaluation Determination of the degree of a physical, mental, or emotional handicap. The diagnosis is applied to legal qualification for benefits and income under disability insurance and to eligibility for Social Security and workmen's compensation benefits. Disability Evaluations,Evaluation, Disability,Evaluations, Disability
D005260 Female Females

Related Publications

Sheera F Lerman, and Zvia Rudich, and Silviu Brill, and Hadar Shalev, and Golan Shahar
January 2015, PloS one,
Sheera F Lerman, and Zvia Rudich, and Silviu Brill, and Hadar Shalev, and Golan Shahar
January 2015, PloS one,
Sheera F Lerman, and Zvia Rudich, and Silviu Brill, and Hadar Shalev, and Golan Shahar
January 2023, International journal of public health,
Sheera F Lerman, and Zvia Rudich, and Silviu Brill, and Hadar Shalev, and Golan Shahar
May 2008, Archives of Iranian medicine,
Sheera F Lerman, and Zvia Rudich, and Silviu Brill, and Hadar Shalev, and Golan Shahar
July 2023, Pain practice : the official journal of World Institute of Pain,
Sheera F Lerman, and Zvia Rudich, and Silviu Brill, and Hadar Shalev, and Golan Shahar
November 2018, Psychiatry research,
Sheera F Lerman, and Zvia Rudich, and Silviu Brill, and Hadar Shalev, and Golan Shahar
December 2019, BMC public health,
Sheera F Lerman, and Zvia Rudich, and Silviu Brill, and Hadar Shalev, and Golan Shahar
December 2020, Injury prevention : journal of the International Society for Child and Adolescent Injury Prevention,
Sheera F Lerman, and Zvia Rudich, and Silviu Brill, and Hadar Shalev, and Golan Shahar
July 2012, Behavior genetics,
Sheera F Lerman, and Zvia Rudich, and Silviu Brill, and Hadar Shalev, and Golan Shahar
July 2006, European journal of pain (London, England),
Copied contents to your clipboard!