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A double-blind crossover study is described of the effect of beclomethasone dipropionate aerosol spray in patients with recurrent (minor) aphthous oral ulceration. Patients included in the study had normal haematological parameters of haemoglobin, ferritin, vitamin B12 and corrected whole blood folate. The design of the study incorporated a washout period and duration of effect was evaluated up to six months. Beclomethasone dipropionate significantly reduced ulcer pain severity and ulcer frequency, but had no significant effect on recurrence of oral ulceration. The preparation was associated with a high patient compliance and has benefit in relieving symptoms in patients with recurrent minor aphthous ulceration.
A C Thompson, and
A Nolan, and
P J Lamey
November 1975,
The Indian journal of medical research,
A C Thompson, and
A Nolan, and
P J Lamey
September 1976,
Chest,
A C Thompson, and
A Nolan, and
P J Lamey
March 1978,
Monatsschrift fur Kinderheilkunde,
A C Thompson, and
A Nolan, and
P J Lamey
February 1987,
British dental journal,
A C Thompson, and
A Nolan, and
P J Lamey
September 1989,
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A C Thompson, and
A Nolan, and
P J Lamey
January 1975,
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A C Thompson, and
A Nolan, and
P J Lamey
June 1976,
Acta allergologica,
A C Thompson, and
A Nolan, and
P J Lamey
January 1975,
Postgraduate medical journal,
A C Thompson, and
A Nolan, and
P J Lamey
May 2001,
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology,
A C Thompson, and
A Nolan, and
P J Lamey
November 1974,
British medical journal,
