BIOMAT Database Logo BIOMAT Database Logo

Translocation t(11;19)(q23;q13.1) without MLL Rearrangement in Acute Myeloid Leukemia: Heterogeneity of the 11q23 Breakpoints. 2015

Katsuya Yamamoto, and Shinichiro Kawamoto, and Seiji Kakiuchi, and Kimikazu Yakushijin, and Hiroshi Matsuoka, and Hironobu Minami
Division of Medical Oncology/Hematology, Department of Medicine, Kobe University Graduate School of Medicine, Kobe, Japan.

UI MeSH Term Description Entries
D009190 Myelodysplastic Syndromes Clonal hematopoietic stem cell disorders characterized by dysplasia in one or more hematopoietic cell lineages. They predominantly affect patients over 60, are considered preleukemic conditions, and have high probability of transformation into ACUTE MYELOID LEUKEMIA. Dysmyelopoietic Syndromes,Hematopoetic Myelodysplasia,Dysmyelopoietic Syndrome,Hematopoetic Myelodysplasias,Myelodysplasia, Hematopoetic,Myelodysplasias, Hematopoetic,Myelodysplastic Syndrome,Syndrome, Dysmyelopoietic,Syndrome, Myelodysplastic,Syndromes, Dysmyelopoietic,Syndromes, Myelodysplastic
D012008 Recurrence The return of a sign, symptom, or disease after a remission. Recrudescence,Relapse,Recrudescences,Recurrences,Relapses
D002880 Chromosomes, Human, Pair 11 A specific pair of GROUP C CHROMOSOMES of the human chromosome classification. Chromosome 11
D002888 Chromosomes, Human, Pair 19 A specific pair of GROUP F CHROMOSOMES of the human chromosome classification. Chromosome 19
D003561 Cytarabine A pyrimidine nucleoside analog that is used mainly in the treatment of leukemia, especially acute non-lymphoblastic leukemia. Cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. Its actions are specific for the S phase of the cell cycle. It also has antiviral and immunosuppressant properties. (From Martindale, The Extra Pharmacopoeia, 30th ed, p472) Ara-C,Arabinofuranosylcytosine,Arabinosylcytosine,Cytosine Arabinoside,Aracytidine,Aracytine,Cytarabine Hydrochloride,Cytonal,Cytosar,Cytosar-U,beta-Ara C,Ara C,Arabinoside, Cytosine,Cytosar U,beta Ara C
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000368 Aged A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available. Elderly
D000971 Antineoplastic Combined Chemotherapy Protocols The use of two or more chemicals simultaneously or sequentially in the drug therapy of neoplasms. The drugs need not be in the same dosage form. Anticancer Drug Combinations,Antineoplastic Agents, Combined,Antineoplastic Chemotherapy Protocols,Antineoplastic Drug Combinations,Cancer Chemotherapy Protocols,Chemotherapy Protocols, Antineoplastic,Drug Combinations, Antineoplastic,Antineoplastic Combined Chemotherapy Regimens,Combined Antineoplastic Agents,Agent, Combined Antineoplastic,Agents, Combined Antineoplastic,Anticancer Drug Combination,Antineoplastic Agent, Combined,Antineoplastic Chemotherapy Protocol,Antineoplastic Drug Combination,Cancer Chemotherapy Protocol,Chemotherapy Protocol, Antineoplastic,Chemotherapy Protocol, Cancer,Chemotherapy Protocols, Cancer,Combinations, Antineoplastic Drug,Combined Antineoplastic Agent,Drug Combination, Anticancer,Drug Combination, Antineoplastic,Drug Combinations, Anticancer,Protocol, Antineoplastic Chemotherapy,Protocol, Cancer Chemotherapy,Protocols, Antineoplastic Chemotherapy,Protocols, Cancer Chemotherapy
D014178 Translocation, Genetic A type of chromosome aberration characterized by CHROMOSOME BREAKAGE and transfer of the broken-off portion to another location, often to a different chromosome. Chromosomal Translocation,Translocation, Chromosomal,Chromosomal Translocations,Genetic Translocation,Genetic Translocations,Translocations, Chromosomal,Translocations, Genetic

Related Publications

Katsuya Yamamoto, and Shinichiro Kawamoto, and Seiji Kakiuchi, and Kimikazu Yakushijin, and Hiroshi Matsuoka, and Hironobu Minami
Congenital Acute Myeloid Leukemia with Unique Translocation t(11;19)(q23;p13.3).
July 2015, Cureus,
Katsuya Yamamoto, and Shinichiro Kawamoto, and Seiji Kakiuchi, and Kimikazu Yakushijin, and Hiroshi Matsuoka, and Hironobu Minami
Childhood acute lymphoblastic leukemia with the MLL-ENL fusion and t(11;19)(q23;p13.3) translocation.
January 1999, Journal of clinical oncology : official journal of the American Society of Clinical Oncology,
Katsuya Yamamoto, and Shinichiro Kawamoto, and Seiji Kakiuchi, and Kimikazu Yakushijin, and Hiroshi Matsuoka, and Hironobu Minami
Heterogeneity in the breakpoints of chromosome 19 among acute leukemic patients with the t(11;19)(q23;p13) translocation.
August 1989, American journal of hematology,
Katsuya Yamamoto, and Shinichiro Kawamoto, and Seiji Kakiuchi, and Kimikazu Yakushijin, and Hiroshi Matsuoka, and Hironobu Minami
Acute myeloid leukemia with associated translocation t(15;17) and 11q23/MLL abnormality.
March 2008, Leukemia & lymphoma,
Katsuya Yamamoto, and Shinichiro Kawamoto, and Seiji Kakiuchi, and Kimikazu Yakushijin, and Hiroshi Matsuoka, and Hironobu Minami
Cloning of several species of MLL/MEN chimeric cDNAs in myeloid leukemia with t(11;19)(q23;p13.1) translocation.
April 1995, Blood,
Katsuya Yamamoto, and Shinichiro Kawamoto, and Seiji Kakiuchi, and Kimikazu Yakushijin, and Hiroshi Matsuoka, and Hironobu Minami
Breakpoints at 11q23 in infant leukemias with the t(11;19)(q23;p13) are clustered.
November 1992, Blood,
Katsuya Yamamoto, and Shinichiro Kawamoto, and Seiji Kakiuchi, and Kimikazu Yakushijin, and Hiroshi Matsuoka, and Hironobu Minami
A case of therapy-related acute lymphoblastic leukemia with t(11;19)(q23;p13.3) and MLL/MLLT1 gene rearrangement.
January 2011, The Korean journal of laboratory medicine,
Katsuya Yamamoto, and Shinichiro Kawamoto, and Seiji Kakiuchi, and Kimikazu Yakushijin, and Hiroshi Matsuoka, and Hironobu Minami
Translocation (4;11)(p12;q23) with rearrangement of FRYL and MLL in therapy-related acute myeloid leukemia.
September 2007, Cancer genetics and cytogenetics,
Katsuya Yamamoto, and Shinichiro Kawamoto, and Seiji Kakiuchi, and Kimikazu Yakushijin, and Hiroshi Matsuoka, and Hironobu Minami
Molecular rearrangement of the MLL gene in adult acute myeloid leukemia without cytogenetic evidence of 11q23 aberration.
January 1996, Cancer genetics and cytogenetics,
Katsuya Yamamoto, and Shinichiro Kawamoto, and Seiji Kakiuchi, and Kimikazu Yakushijin, and Hiroshi Matsuoka, and Hironobu Minami
Cloning of ELL, a gene that fuses to MLL in a t(11;19)(q23;p13.1) in acute myeloid leukemia.
December 1994, Proceedings of the National Academy of Sciences of the United States of America,
Copied contents to your clipboard!