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Laminin, an integral component of basement membranes, consists of three subunit polypeptides, A, B1, and B2 chains. We have recently isolated cDNAs corresponding to human laminin A chain. These cDNAs were utilized for chromosomal in situ hybridizations to establish the genomic location of the laminin A chain gene. Metaphase chromosomes of PHA-stimulated human peripheral blood leukocytes were examined by in situ hybridization with 3H-labeled cDNAs, and the chromosomes were identified by R-banding (fluorochrome-photolysis-Giemsa method). The results indicated that the human laminin A chain is at locus 18p11.3. Since human laminin B1 and B2 chain genes have been previously mapped to chromosomes 7 and 1, respectively, the results indicate that genes encoding human laminin chains reside in separate chromosomes.
T Nagayoshi, and
M G Mattei, and
E Passage, and
R Knowlton, and
M L Chu, and
J Uitto
January 1996,
Immunogenetics,
T Nagayoshi, and
M G Mattei, and
E Passage, and
R Knowlton, and
M L Chu, and
J Uitto
August 2010,
Clinical and experimental dermatology,
T Nagayoshi, and
M G Mattei, and
E Passage, and
R Knowlton, and
M L Chu, and
J Uitto
February 1995,
Matrix biology : journal of the International Society for Matrix Biology,
T Nagayoshi, and
M G Mattei, and
E Passage, and
R Knowlton, and
M L Chu, and
J Uitto
November 2004,
The Journal of investigative dermatology,
T Nagayoshi, and
M G Mattei, and
E Passage, and
R Knowlton, and
M L Chu, and
J Uitto
January 1991,
The Journal of biological chemistry,
T Nagayoshi, and
M G Mattei, and
E Passage, and
R Knowlton, and
M L Chu, and
J Uitto
September 1982,
Proceedings of the National Academy of Sciences of the United States of America,
T Nagayoshi, and
M G Mattei, and
E Passage, and
R Knowlton, and
M L Chu, and
J Uitto
August 1987,
The Journal of biological chemistry,
T Nagayoshi, and
M G Mattei, and
E Passage, and
R Knowlton, and
M L Chu, and
J Uitto
September 1990,
The Journal of biological chemistry,
T Nagayoshi, and
M G Mattei, and
E Passage, and
R Knowlton, and
M L Chu, and
J Uitto
November 1992,
The Journal of cell biology,
T Nagayoshi, and
M G Mattei, and
E Passage, and
R Knowlton, and
M L Chu, and
J Uitto
September 1994,
Genomics,
