-transparent.png){kind=logo}
We report the case of a 26-yr-old patient with fulminant liver failure and acute hemorrhagic pancreatitis secondary to the use of trimethoprim-sulfamethoxazole (Bactrim DS). Our patient presented with skin rash and decreased C3 and C4 levels, which we believed was due to a hypersensitivity reaction secondary to the sulfonamide component (sulfamethoxazole). To our knowledge, this is the first case reported in which sulfamethoxazole-trimethoprim has been implicated as a cause of fulminant liver failure and acute hemorrhagic pancreatitis simultaneously, and emphasizes the need of discontinuing this medication as soon as there is evidence of liver and pancreatic dysfunction.
Related Publications
J J Alberti-Flor, and
M E Hernandez, and
J P Ferrer, and
S Howell, and
L Jeffers
October 2003,
Clinical transplantation,
J J Alberti-Flor, and
M E Hernandez, and
J P Ferrer, and
S Howell, and
L Jeffers
March 1986,
Annals of internal medicine,
J J Alberti-Flor, and
M E Hernandez, and
J P Ferrer, and
S Howell, and
L Jeffers
April 2021,
American journal of respiratory and critical care medicine,
J J Alberti-Flor, and
M E Hernandez, and
J P Ferrer, and
S Howell, and
L Jeffers
January 1999,
The American journal of gastroenterology,
J J Alberti-Flor, and
M E Hernandez, and
J P Ferrer, and
S Howell, and
L Jeffers
February 2001,
The Pediatric infectious disease journal,
J J Alberti-Flor, and
M E Hernandez, and
J P Ferrer, and
S Howell, and
L Jeffers
May 2013,
Singapore medical journal,
J J Alberti-Flor, and
M E Hernandez, and
J P Ferrer, and
S Howell, and
L Jeffers
December 2000,
Archives of pathology & laboratory medicine,
J J Alberti-Flor, and
M E Hernandez, and
J P Ferrer, and
S Howell, and
L Jeffers
June 2017,
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists,
J J Alberti-Flor, and
M E Hernandez, and
J P Ferrer, and
S Howell, and
L Jeffers
July 2008,
Cases journal,
J J Alberti-Flor, and
M E Hernandez, and
J P Ferrer, and
S Howell, and
L Jeffers
March 2005,
Digestive diseases and sciences,
