-transparent.png){kind=logo}
A rare primary argyrophilic carcinoma "carcinoid tumor" of the breast in a 48-year-old woman was investigated by light and electron microscopy, and immunohistochemistry. Light microscopy showed the greater part of the tumor to have characteristic histological features of carcinoid tumor and Grimerius' stain revealed the presence of numerous argyrophilic granules in the tumor cells. Numerous neurosecretory granules and bundles of intermediate filaments were observed ultrastructurally in the cytoplasm. In addition, carcinoembryonic antigen (CEA) and neuronespecific enolase (NSE) were detected in the tumor cells using the immunoperoxidase method. From the results, it is speculated that the tumor cells have the ability to produce CEA as well as NSE in the cytoplasm. The observation of ductal spreading in parts of the tumor, and the detection of CEA, suggest the tumor cells to be derived from mammary epithelial cells.
M Kurosumi, and
C Nomoto, and
K Suemasu, and
Y Higashi, and
K Takubo, and
S Takayama
November 1988,
Acta pathologica japonica,
M Kurosumi, and
C Nomoto, and
K Suemasu, and
Y Higashi, and
K Takubo, and
S Takayama
June 1988,
Tumori,
M Kurosumi, and
C Nomoto, and
K Suemasu, and
Y Higashi, and
K Takubo, and
S Takayama
February 1991,
American journal of clinical pathology,
M Kurosumi, and
C Nomoto, and
K Suemasu, and
Y Higashi, and
K Takubo, and
S Takayama
July 1985,
Human pathology,
M Kurosumi, and
C Nomoto, and
K Suemasu, and
Y Higashi, and
K Takubo, and
S Takayama
February 1985,
Cancer,
M Kurosumi, and
C Nomoto, and
K Suemasu, and
Y Higashi, and
K Takubo, and
S Takayama
January 1999,
Clinical and experimental obstetrics & gynecology,
M Kurosumi, and
C Nomoto, and
K Suemasu, and
Y Higashi, and
K Takubo, and
S Takayama
May 1995,
Cancer control : journal of the Moffitt Cancer Center,
M Kurosumi, and
C Nomoto, and
K Suemasu, and
Y Higashi, and
K Takubo, and
S Takayama
August 1988,
The American journal of surgical pathology,
M Kurosumi, and
C Nomoto, and
K Suemasu, and
Y Higashi, and
K Takubo, and
S Takayama
June 1982,
Human pathology,
M Kurosumi, and
C Nomoto, and
K Suemasu, and
Y Higashi, and
K Takubo, and
S Takayama
January 2003,
Ultrastructural pathology,
