Biomaterial Database

Echocardiographic evaluation of vagolytic effects of hyoscine butylbromide in paediatric halothane anaesthesia. 1989

M Yamashita, and H Horigome

The effects of vagolysis with hyoscine butylbromide on left ventricular function were evaluated by echocardiography during halothane anaesthesia in children. Echocardiography showed deterioration of the following values after halothane induction; pre-ejection period, systolic time interval, left ventricular shortening fraction and ejection fraction. The first two values were improved by vagolysls with hyoscine butylbromide. However, relatively rate-independent indices, i.e. left ventricular shortening fraction and ejection fraction, still remained depressed even after vagolysis with hyoscine butylbromide. This implies that halothane-induced myocardial depression can only be partially antagonized by vagolysis.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D002086	Butylscopolammonium Bromide	Antimuscarinic quaternary ammonium derivative of scopolamine used to treat cramps in gastrointestinal, urinary, uterine, and biliary tracts, and to facilitate radiologic visualization of the gastrointestinal tract.	Hyoscinbutylbromide,Scopolaminebutylbromide,Buscapine,Buscolysin,Buscopan,Butylscopolamine,Hyoscine N-Butylbromide,N-Butylscopolammonium Bromide,Scopolan,Bromide, Butylscopolammonium,Bromide, N-Butylscopolammonium,Hyoscine N Butylbromide,N Butylscopolammonium Bromide,N-Butylbromide, Hyoscine
D002648	Child	A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL.	Children
D002675	Child, Preschool	A child between the ages of 2 and 5.	Children, Preschool,Preschool Child,Preschool Children
D004452	Echocardiography	Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues. The standard approach is transthoracic.	Echocardiography, Contrast,Echocardiography, Cross-Sectional,Echocardiography, M-Mode,Echocardiography, Transthoracic,Echocardiography, Two-Dimensional,Transthoracic Echocardiography,2-D Echocardiography,2D Echocardiography,Contrast Echocardiography,Cross-Sectional Echocardiography,Echocardiography, 2-D,Echocardiography, 2D,M-Mode Echocardiography,Two-Dimensional Echocardiography,2 D Echocardiography,Cross Sectional Echocardiography,Echocardiography, 2 D,Echocardiography, Cross Sectional,Echocardiography, M Mode,Echocardiography, Two Dimensional,M Mode Echocardiography,Two Dimensional Echocardiography
D005260	Female		Females
D006221	Halothane	A nonflammable, halogenated, hydrocarbon anesthetic that provides relatively rapid induction with little or no excitement. Analgesia may not be adequate. NITROUS OXIDE is often given concomitantly. Because halothane may not produce sufficient muscle relaxation, supplemental neuromuscular blocking agents may be required. (From AMA Drug Evaluations Annual, 1994, p178)	1,1,1-Trifluoro-2-Chloro-2-Bromoethane,Fluothane,Ftorotan,Narcotan
D006439	Hemodynamics	The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM.	Hemodynamic
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000769	Anesthesia, Inhalation	Anesthesia caused by the breathing of anesthetic gases or vapors or by insufflating anesthetic gases or vapors into the respiratory tract.	Insufflation Anesthesia,Anesthesia, Insufflation,Inhalation Anesthesia