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A total of 89 subjects including 30 breast cancer patients with distal metastases, 29 patients with benign breast disease, and 30 healthy subjects were studied. Serum samples from these subjects were obtained from the National Cancer Institute (NCI) Breast Cancer Serum Bank, Bethesda. Serum concentrations of vitamin A and its transport proteins (prealbumin and retinol-binding protein [RBP]), beta-carotene, vitamin E, and selenium were determined. For each of these parameters the mean for the breast cancer patients was lower than that of the healthy subjects. The differences between healthy subjects and patients with either breast cancer or benign breast disease were, however, statistically significant only in the case of RBP (p less than 0.05). In the case of vitamin A and its transport proteins these differences were reduced by comparing the cancer patients with the benign breast disease patients rather than with the healthy controls. This indicates that the low serum levels for those three parameters may be merely a consequence of disease in general rather than a feature of cancer per se.
T K Basu, and
G B Hill, and
D Ng, and
E Abdi, and
N Temple
November 1986,
The New England journal of medicine,
T K Basu, and
G B Hill, and
D Ng, and
E Abdi, and
N Temple
January 1987,
Archives of gynecology and obstetrics,
T K Basu, and
G B Hill, and
D Ng, and
E Abdi, and
N Temple
November 2003,
Biological trace element research,
T K Basu, and
G B Hill, and
D Ng, and
E Abdi, and
N Temple
January 2010,
Current eye research,
T K Basu, and
G B Hill, and
D Ng, and
E Abdi, and
N Temple
January 1973,
Sbornik vedeckych praci Lekarske fakulty Karlovy univerzity v Hradci Kralove. Supplementum,
T K Basu, and
G B Hill, and
D Ng, and
E Abdi, and
N Temple
January 1990,
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery,
T K Basu, and
G B Hill, and
D Ng, and
E Abdi, and
N Temple
January 1994,
International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition,
T K Basu, and
G B Hill, and
D Ng, and
E Abdi, and
N Temple
January 1992,
American journal of epidemiology,
T K Basu, and
G B Hill, and
D Ng, and
E Abdi, and
N Temple
January 1997,
British journal of cancer,
T K Basu, and
G B Hill, and
D Ng, and
E Abdi, and
N Temple
September 1992,
Annals of the New York Academy of Sciences,
