BIOMAT Database Logo BIOMAT Database Logo

The number and characteristics of prevalent vertebral fractures in elderly men are associated with low bone mass and osteoporosis. 2015

M Kherad, and D Mellström, and B E Rosengren, and R Hasserius, and J-Å Nilsson, and I Redlund-Johnell, and C Ohlsson, and M Lorentzon, and M K Karlsson
Skåne University Hospital, SE-20502, Malmo, Sweden.

We sought to determine whether specific characteristics of vertebral fractures in elderly men are associated with low bone mineral density (BMD) and osteoporosis. Mister Osteoporosis Sweden is a population based cohort study involving 3014 men aged 69 to 81 years. Of these, 1427 had readable lateral radiographs of the thoracic and lumbar spine. Total body (TB) BMD (g/cm²) and total right hip (TH) BMD were measured by dual energy x-ray absorptiometry. The proportion of men with osteoporosis was calculated from TH BMD. There were 215 men (15.1%) with a vertebral fracture. Those with a fracture had lower TB BMD than those without (p < 0.001). Among men with a fracture, TB BMD was lower in those with more than three fractures (p = 0.02), those with biconcave fractures (p = 0.02) and those with vertebral body compression of > 42% (worst quartile) (p = 0.03). The mean odds ratio (OR) for having osteoporosis when having any type of vertebral fracture was 6.1 (95% confidence interval (CI) 3.9 to 9.5) compared with those without a fracture. A combination of more than three fractures and compression in the worst quartile had a mean OR of 114.2 (95% CI 6.7 to 1938.3) of having osteoporosis compared with those without a fracture. We recommend BMD studies to be undertaken in these subcohorts of elderly men with a vertebral fracture.

UI MeSH Term Description Entries
D008159 Lumbar Vertebrae VERTEBRAE in the region of the lower BACK below the THORACIC VERTEBRAE and above the SACRAL VERTEBRAE. Vertebrae, Lumbar
D008297 Male Males
D010024 Osteoporosis Reduction of bone mass without alteration in the composition of bone, leading to fractures. Primary osteoporosis can be of two major types: postmenopausal osteoporosis (OSTEOPOROSIS, POSTMENOPAUSAL) and age-related or senile osteoporosis. Age-Related Osteoporosis,Bone Loss, Age-Related,Osteoporosis, Age-Related,Osteoporosis, Post-Traumatic,Osteoporosis, Senile,Senile Osteoporosis,Osteoporosis, Involutional,Age Related Osteoporosis,Age-Related Bone Loss,Age-Related Bone Losses,Age-Related Osteoporoses,Bone Loss, Age Related,Bone Losses, Age-Related,Osteoporoses,Osteoporoses, Age-Related,Osteoporoses, Senile,Osteoporosis, Age Related,Osteoporosis, Post Traumatic,Post-Traumatic Osteoporoses,Post-Traumatic Osteoporosis,Senile Osteoporoses
D011446 Prospective Studies Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group. Prospective Study,Studies, Prospective,Study, Prospective
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000368 Aged A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available. Elderly
D000369 Aged, 80 and over Persons 80 years of age and older. Oldest Old
D012307 Risk Factors An aspect of personal behavior or lifestyle, environmental exposure, inborn or inherited characteristic, which, based on epidemiological evidence, is known to be associated with a health-related condition considered important to prevent. Health Correlates,Risk Factor Scores,Risk Scores,Social Risk Factors,Population at Risk,Populations at Risk,Correlates, Health,Factor, Risk,Factor, Social Risk,Factors, Social Risk,Risk Factor,Risk Factor Score,Risk Factor, Social,Risk Factors, Social,Risk Score,Score, Risk,Score, Risk Factor,Social Risk Factor
D013548 Sweden Country in northern Europe, bordering the Baltic Sea, between Finland and Norway. The capital is Stockholm.
D015502 Absorptiometry, Photon A noninvasive method for assessing BODY COMPOSITION. It is based on the differential absorption of X-RAYS (or GAMMA RAYS) by different tissues such as bone, fat and other soft tissues. The source of (X-ray or gamma-ray) photon beam is generated either from radioisotopes such as GADOLINIUM 153, IODINE 125, or Americanium 241 which emit GAMMA RAYS in the appropriate range; or from an X-ray tube which produces X-RAYS in the desired range. It is primarily used for quantitating BONE MINERAL CONTENT, especially for the diagnosis of OSTEOPOROSIS, and also in measuring BONE MINERALIZATION. Absorptiometry, X-Ray,Dual-Photon Absorptiometry,Photodensitometry, X-Ray,Photon Absorptiometry,Single-Photon Absorptiometry,X-Ray Absorptiometry,Absorptiometry, Dual X-Ray,Absorptiometry, Dual-Energy Radiographic,Absorptiometry, Dual-Energy X-Ray,DEXA Scan,DPX Absorptiometry,DXA Scan,Densitometry, X-Ray,Densitometry, Xray,Dual X-Ray Absorptiometry,Dual-Energy Radiographic Absorptiometry,Dual-Energy X-Ray Absorptiometry,Dual-Energy X-Ray Absorptiometry Scan,Radiographic Absorptiometry, Dual-Energy,X-Ray Absorptiometry, Dual-Energy,X-Ray Photodensitometry,Absorptiometries, DPX,Absorptiometry, DPX,Absorptiometry, Dual Energy Radiographic,Absorptiometry, Dual Energy X Ray,Absorptiometry, Dual X Ray,Absorptiometry, Dual-Photon,Absorptiometry, Single-Photon,Absorptiometry, X Ray,DEXA Scans,DXA Scans,Densitometry, X Ray,Dual Energy Radiographic Absorptiometry,Dual Energy X Ray Absorptiometry,Dual Energy X Ray Absorptiometry Scan,Dual Photon Absorptiometry,Dual X Ray Absorptiometry,Photodensitometry, X Ray,Radiographic Absorptiometry, Dual Energy,Scan, DEXA,Scan, DXA,Scans, DEXA,Scans, DXA,Single Photon Absorptiometry,X Ray Absorptiometry,X Ray Absorptiometry, Dual Energy,X Ray Photodensitometry,X-Ray Absorptiometry, Dual,X-Ray Densitometry,Xray Densitometry

Related Publications

M Kherad, and D Mellström, and B E Rosengren, and R Hasserius, and J-Å Nilsson, and I Redlund-Johnell, and C Ohlsson, and M Lorentzon, and M K Karlsson
Hyperkyphosis and back pain are not associated with prevalent vertebral fractures in women with osteoporosis.
March 2015, Physiotherapy theory and practice,
M Kherad, and D Mellström, and B E Rosengren, and R Hasserius, and J-Å Nilsson, and I Redlund-Johnell, and C Ohlsson, and M Lorentzon, and M K Karlsson
[Study of the bone mass in osteoporosis with vertebral fractures].
June 1972, Revista medica de Chile,
M Kherad, and D Mellström, and B E Rosengren, and R Hasserius, and J-Å Nilsson, and I Redlund-Johnell, and C Ohlsson, and M Lorentzon, and M K Karlsson
Vertebral fractures are associated with increased cortical porosity in iliac crest bone biopsy of men with idiopathic osteoporosis.
March 2009, Bone,
M Kherad, and D Mellström, and B E Rosengren, and R Hasserius, and J-Å Nilsson, and I Redlund-Johnell, and C Ohlsson, and M Lorentzon, and M K Karlsson
Bone mineral density and prevalent vertebral fractures in men and women.
January 2004, Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA,
M Kherad, and D Mellström, and B E Rosengren, and R Hasserius, and J-Å Nilsson, and I Redlund-Johnell, and C Ohlsson, and M Lorentzon, and M K Karlsson
Vertebral fractures in men and women: how discriminative are bone mass measurements?
June 1995, The British journal of radiology,
M Kherad, and D Mellström, and B E Rosengren, and R Hasserius, and J-Å Nilsson, and I Redlund-Johnell, and C Ohlsson, and M Lorentzon, and M K Karlsson
Echogenic carotid artery plaques are associated with vertebral fractures in postmenopausal women with low bone mass.
June 2008, Calcified tissue international,
M Kherad, and D Mellström, and B E Rosengren, and R Hasserius, and J-Å Nilsson, and I Redlund-Johnell, and C Ohlsson, and M Lorentzon, and M K Karlsson
Are we missing osteoporosis-related vertebral fractures in men?
June 2011, Asian spine journal,
M Kherad, and D Mellström, and B E Rosengren, and R Hasserius, and J-Å Nilsson, and I Redlund-Johnell, and C Ohlsson, and M Lorentzon, and M K Karlsson
Early smoking is associated with peak bone mass and prevalent fractures in young, healthy men.
February 2010, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research,
M Kherad, and D Mellström, and B E Rosengren, and R Hasserius, and J-Å Nilsson, and I Redlund-Johnell, and C Ohlsson, and M Lorentzon, and M K Karlsson
Number and severity of prevalent vertebral fractures and the risk of subsequent vertebral fractures in Japanese women with osteoporosis: results from the minodronate trial.
September 2013, Journal of bone and mineral metabolism,
M Kherad, and D Mellström, and B E Rosengren, and R Hasserius, and J-Å Nilsson, and I Redlund-Johnell, and C Ohlsson, and M Lorentzon, and M K Karlsson
Bone mineral density and bone size in men with primary osteoporosis and vertebral fractures.
May 1998, Calcified tissue international,
Copied contents to your clipboard!