Biomaterial Database

Effects of d-amphetamine on choice of social versus monetary reinforcement: a discrete-trial test. 1989

S T Higgins, and J R Hughes, and W K Bickel

Department of Psychiatry, University of Vermont, Burlington 05401.

Two mutually exclusive options were concurrently available to eight volunteers during 60-min experimental sessions. Subjects chose every three minutes between conversing with another same-sex volunteer and providing speech monologues for monetary reinforcement. d-Amphetamine (12.5 and 25 mg/70 kg) significantly increased choice of social over monetary reinforcement. Drug-produced increases in choice of the social option were associated with increases in total seconds of speech and the rate of social conversation. d-Amphetamine also increased subject ratings of effects indicative of greater sociability such as friendliness, elation and energetic. These results suggest that d-amphetamine can increase the relative reinforcing effects of social interaction.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D012054	Reinforcement, Psychology	The strengthening of a conditioned response.	Negative Reinforcement,Positive Reinforcement,Psychological Reinforcement,Reinforcement (Psychology),Negative Reinforcements,Positive Reinforcements,Psychological Reinforcements,Psychology Reinforcement,Psychology Reinforcements,Reinforcement, Negative,Reinforcement, Positive,Reinforcement, Psychological,Reinforcements (Psychology),Reinforcements, Negative,Reinforcements, Positive,Reinforcements, Psychological,Reinforcements, Psychology
D012056	Reinforcement, Social	The strengthening of a response with a social reward such as a nod of approval, a parent's love or attention.	Social Reinforcement,Reinforcements, Social,Social Reinforcements
D002755	Choice Behavior	The act of making a selection among two or more alternatives, usually after a period of deliberation.	Approach Behavior,Approach Behaviors,Behavior, Approach,Behavior, Choice,Behaviors, Approach,Behaviors, Choice,Choice Behaviors
D003913	Dextroamphetamine	The d-form of AMPHETAMINE. It is a central nervous system stimulant and a sympathomimetic. It has also been used in the treatment of narcolepsy and of attention deficit disorders and hyperactivity in children. Dextroamphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulating release of monamines, and inhibiting monoamine oxidase. It is also a drug of abuse and a psychotomimetic.	d-Amphetamine,Curban,Dexamfetamine,Dexamphetamine,Dexedrine,Dextro-Amphetamine Sulfate,DextroStat,Dextroamphetamine Sulfate,Oxydess,d-Amphetamine Sulfate,dextro-Amphetamine,Dextro Amphetamine Sulfate,Sulfate, Dextroamphetamine,d Amphetamine,d Amphetamine Sulfate,dextro Amphetamine
D004305	Dose-Response Relationship, Drug	The relationship between the dose of an administered drug and the response of the organism to the drug.	Dose Response Relationship, Drug,Dose-Response Relationships, Drug,Drug Dose-Response Relationship,Drug Dose-Response Relationships,Relationship, Drug Dose-Response,Relationships, Drug Dose-Response
D004467	Economics	The science of utilization, distribution, and consumption of services and materials.	Consumer Price Index,Capital,Conditions, Economic,Consumption,Cost of Living,Easterlin Hypothesis,Economic Conditions,Economic Policies,Economic Policy,Economics, Home,Home Economics,Household Consumption,Macroeconomic Factors,Microeconomic Factors,Policies, Economic,Policy, Economic,Production,Remittances,Utility Theory,Condition, Economic,Consumer Price Indices,Consumption, Household,Economic Condition,Factor, Macroeconomic,Factor, Microeconomic,Factors, Macroeconomic,Factors, Microeconomic,Household Consumptions,Hypothesis, Easterlin,Index, Consumer Price,Indices, Consumer Price,Living Cost,Living Costs,Remittance,Theories, Utility,Theory, Utility,Utility Theories
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man