-transparent.png){kind=logo}
The ultrastructural localization of immunoglobulins (IgG, IgA, IgM), complement component (C3c), or fibrinogen-related antigen (FRA) was investigated on 5 biopsy samples from 5 children with idiopathic MN or lupus nephritis using protein A-gold (PAG) complex method. The immunoreactivity of IgG was essentially confined to the mesangial and subepithelial electron-dense deposit (EDD) in all of 5 children, and more intense staining of IgG was observed in 3 children with stage II of MN than those with stage I and stage III of MN. Double immunocytochemical staining showed the same distribution of both IgG and IgM or both IgG and FRA in subepithelial EDD in 2 of 5 children. These findings suggest that IgG deposits are associated with the formation of subepithelial EDD in MN, and raise the possibility that IgM and FRA deposits may result from entrapment and/or immunological reaction.
S Kawahara, and
T Matsunaga, and
S Sakamoto, and
K Taira, and
H Kamitsuji, and
M Nakajima
January 1987,
Nephron,
S Kawahara, and
T Matsunaga, and
S Sakamoto, and
K Taira, and
H Kamitsuji, and
M Nakajima
January 1989,
Virchows Archiv. A, Pathological anatomy and histopathology,
S Kawahara, and
T Matsunaga, and
S Sakamoto, and
K Taira, and
H Kamitsuji, and
M Nakajima
November 1988,
Nihon Jinzo Gakkai shi,
S Kawahara, and
T Matsunaga, and
S Sakamoto, and
K Taira, and
H Kamitsuji, and
M Nakajima
January 1986,
[Hokkaido igaku zasshi] The Hokkaido journal of medical science,
S Kawahara, and
T Matsunaga, and
S Sakamoto, and
K Taira, and
H Kamitsuji, and
M Nakajima
January 1985,
Ultrastructural pathology,
S Kawahara, and
T Matsunaga, and
S Sakamoto, and
K Taira, and
H Kamitsuji, and
M Nakajima
September 1987,
Cancer,
S Kawahara, and
T Matsunaga, and
S Sakamoto, and
K Taira, and
H Kamitsuji, and
M Nakajima
January 1987,
Ultrastructural pathology,
S Kawahara, and
T Matsunaga, and
S Sakamoto, and
K Taira, and
H Kamitsuji, and
M Nakajima
January 1984,
Nephron,
S Kawahara, and
T Matsunaga, and
S Sakamoto, and
K Taira, and
H Kamitsuji, and
M Nakajima
March 1988,
Zhonghua bing li xue za zhi = Chinese journal of pathology,
S Kawahara, and
T Matsunaga, and
S Sakamoto, and
K Taira, and
H Kamitsuji, and
M Nakajima
January 1984,
Histochemistry,
