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The effect of two doses of oxytocin (2 or 4 UI/kg i.p.) has been studied in the male Wistar rats, either preceded or not by a naloxone administration (10 mg/kg i.p.), on the response of the hypothalamus-pituitary-adrenal system, the latter being valued by changes produced in the plasmatic corticosterone levels. Oxytocin produced significant increases of the plasmatic corticosterone levels, this effect being stronger and longer lasting after the superior dose. Naloxone alone produced the same effect, but not as intense and stable as that of oxytocin. Pretreatment with naloxone modified the response of the hypothalamus-pituitary-adrenal system to oxytocin, producing partial blockade. The results suggest that the oxytocin action on the hypothalamus-pituitary-adrenal axis might be mediated by the endogenous opiates.
P Montilla, and
J L Muñoz, and
J E Ríos, and
M C Muñoz
November 1969,
The Journal of pharmacy and pharmacology,
P Montilla, and
J L Muñoz, and
J E Ríos, and
M C Muñoz
March 1980,
Life sciences,
P Montilla, and
J L Muñoz, and
J E Ríos, and
M C Muñoz
January 1970,
Problemy endokrinologii,
P Montilla, and
J L Muñoz, and
J E Ríos, and
M C Muñoz
February 1981,
Chemical & pharmaceutical bulletin,
P Montilla, and
J L Muñoz, and
J E Ríos, and
M C Muñoz
October 1988,
Pharmacology & toxicology,
P Montilla, and
J L Muñoz, and
J E Ríos, and
M C Muñoz
January 1986,
Psychoneuroendocrinology,
P Montilla, and
J L Muñoz, and
J E Ríos, and
M C Muñoz
October 1984,
Life sciences,
P Montilla, and
J L Muñoz, and
J E Ríos, and
M C Muñoz
January 1984,
Psychopharmacology,
P Montilla, and
J L Muñoz, and
J E Ríos, and
M C Muñoz
July 1966,
The Journal of pharmacology and experimental therapeutics,
P Montilla, and
J L Muñoz, and
J E Ríos, and
M C Muñoz
March 1979,
Pharmacology, biochemistry, and behavior,
