BIOMAT Database Logo BIOMAT Database Logo

[Characteristics of concanavalin A-binding neurospecific glycoproteins from various regions of the rat brain during experimental neurosis]. 1989

V A Berezin, and G M Shevchenko, and P A Nerush, and G A Ushakova, and O V Polishenko

The polypeptide composition of neurospecific glycoproteins in different areas of the rat brain under experimental neurosis is characterized using SDS-PAG-electrophoresis followed by electroblot and immunofixation on nitrocellulose membranes. The soluble and membrane-bound glycoproteins are purified by Con A-Sepharose column chromatography. Changes in the glycoprotein polypeptide composition in different areas of the rat brain under experimental neurosis are qualitative. Soluble glycopolypeptide 27 kDa and membrane glycopolypeptide 32 kDa are not revealed in the midbrain and corpus striatum. Soluble polypeptide 47 kDa is absent in the cerebral cortex and hippocampus. It is suggested that the above mentioned glycopolypeptides are important for the CNS physiological functioning.

UI MeSH Term Description Entries
D008970 Molecular Weight The sum of the weight of all the atoms in a molecule. Molecular Weights,Weight, Molecular,Weights, Molecular
D009419 Nerve Tissue Proteins Proteins, Nerve Tissue,Tissue Proteins, Nerve
D009497 Neurotic Disorders Disorders in which the symptoms are distressing to the individual and recognized by him or her as being unacceptable. Social relationships may be greatly affected but usually remain within acceptable limits. The disturbance is relatively enduring or recurrent without treatment. Neuroses,Psychoneuroses,Disorder, Neurotic,Disorders, Neurotic,Neurotic Disorder
D010455 Peptides Members of the class of compounds composed of AMINO ACIDS joined together by peptide bonds between adjacent amino acids into linear, branched or cyclical structures. OLIGOPEPTIDES are composed of approximately 2-12 amino acids. Polypeptides are composed of approximately 13 or more amino acids. PROTEINS are considered to be larger versions of peptides that can form into complex structures such as ENZYMES and RECEPTORS. Peptide,Polypeptide,Polypeptides
D011952 Receptors, Concanavalin A Glycoprotein moieties on the surfaces of cell membranes that bind concanavalin A selectively; the number and location of the sites depends on the type and condition of the cell. Concanavalin A Binding Sites,Concanavalin A Receptors,Concanavalin A Receptor,Receptor, Concanavalin A
D001921 Brain The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM. Encephalon
D006023 Glycoproteins Conjugated protein-carbohydrate compounds including MUCINS; mucoid, and AMYLOID glycoproteins. C-Glycosylated Proteins,Glycosylated Protein,Glycosylated Proteins,N-Glycosylated Proteins,O-Glycosylated Proteins,Glycoprotein,Neoglycoproteins,Protein, Glycosylated,Proteins, C-Glycosylated,Proteins, Glycosylated,Proteins, N-Glycosylated,Proteins, O-Glycosylated
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D014018 Tissue Distribution Accumulation of a drug or chemical substance in various organs (including those not relevant to its pharmacologic or therapeutic action). This distribution depends on the blood flow or perfusion rate of the organ, the ability of the drug to penetrate organ membranes, tissue specificity, protein binding. The distribution is usually expressed as tissue to plasma ratios. Distribution, Tissue,Distributions, Tissue,Tissue Distributions
D051381 Rats The common name for the genus Rattus. Rattus,Rats, Laboratory,Rats, Norway,Rattus norvegicus,Laboratory Rat,Laboratory Rats,Norway Rat,Norway Rats,Rat,Rat, Laboratory,Rat, Norway,norvegicus, Rattus

Related Publications

V A Berezin, and G M Shevchenko, and P A Nerush, and G A Ushakova, and O V Polishenko
Concanavalin A-binding glycopeptides from rat brain glycoproteins.
December 1975, Neurobiology,
V A Berezin, and G M Shevchenko, and P A Nerush, and G A Ushakova, and O V Polishenko
Isolation of concanavalin A-binding glycoproteins from rat brain.
June 1973, FEBS letters,
V A Berezin, and G M Shevchenko, and P A Nerush, and G A Ushakova, and O V Polishenko
Preparation and properties of concanavalin A-binding glycopeptides derived from rat brain glycoproteins.
September 1975, Biochimica et biophysica acta,
V A Berezin, and G M Shevchenko, and P A Nerush, and G A Ushakova, and O V Polishenko
Concanavalin A binding glycoproteins in subcellular fractions from the developing rat cerebral cortex.
September 1984, Journal of neurochemistry,
V A Berezin, and G M Shevchenko, and P A Nerush, and G A Ushakova, and O V Polishenko
Characterization of concanavalin A-binding neuronal and glial surface glycoproteins from human foetal brain.
June 1992, Indian journal of biochemistry & biophysics,
V A Berezin, and G M Shevchenko, and P A Nerush, and G A Ushakova, and O V Polishenko
Concanavalin A binding glycoproteins of epidermal cells.
September 1982, The Journal of investigative dermatology,
V A Berezin, and G M Shevchenko, and P A Nerush, and G A Ushakova, and O V Polishenko
Major differences in the concanavalin A binding glycoproteins of postsynaptic densities from rat forebrain and cerebellum.
October 1983, Brain research,
V A Berezin, and G M Shevchenko, and P A Nerush, and G A Ushakova, and O V Polishenko
Identification of concanavalin A binding glycoproteins of rat liver cell nuclear membranes.
October 1977, Biochemical and biophysical research communications,
V A Berezin, and G M Shevchenko, and P A Nerush, and G A Ushakova, and O V Polishenko
Structure of the mannose-rich oligosaccharide chains of concanavalin A-binding glycopeptides derived from beef brain glycoproteins.
August 1983, Journal of neurochemistry,
V A Berezin, and G M Shevchenko, and P A Nerush, and G A Ushakova, and O V Polishenko
A study of 3H-L-flucose-containing glycoproteins of the crude synaptosomal fraction obtained from rat brain regions at various ages.
January 1976, Journal of neuroscience research,
Copied contents to your clipboard!